Efficient Conversion of Pyruvic Aldehyde into Lactic Acid by Lewis Acid Catalyst in Water

• Yusuke Koito

  Materials and Structures Laboratory, Tokyo Institute of Technology

• Kiyotaka Nakajima

  Materials and Structures Laboratory, Tokyo Institute of Technology

• Masaaki Kitano

  Materials and Structures Laboratory, Tokyo Institute of Technology

• Michikazu Hara

  Materials and Structures Laboratory, Tokyo Institute of Technology

Abstract

Homogeneous and heterogeneous catalysts with water-tolerant Lewis acids, such as Sc(OTf)3 and Nb2O5·nH2O, effectively promote the hydride transfer of pyruvic aldehyde into lactic acid in water at 383 K, whereas Brønsted acid catalysts cannot function as effective catalysts under mild conditions. NMR measurement in the presence of D2O suggests that the reaction on a Lewis acid catalyst proceeds via the Meerwein–Ponndorf–Verley (MPV) reduction.

Journal

• Chemistry Letters

  Chemistry Letters 42 (8), 873-875, 2013-05-29

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360002219105396352
• NII Article ID: 10031189280
• NII Book ID: AA00603318
• DOI: 10.1246/cl.130319
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/42/8/873/55635885/cl.130319.pdf
• Data Source:
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