Role of Hydrogen Bond Connecting Ligands for Substrate and Type I Copper in Copper(I) Oxidase CueO

• Kunishige Kataoka

  Graduate School of Natural Science and Technology, Kanazawa University

• Takeshi Sakurai

  Graduate School of Natural Science and Technology, Kanazawa University

Abstract

Mutational and kinetic studies on Asp439, a ligand for the substrate-binding site in the copper(I) oxidase—CueO—and the deletion mutant—Δα5–7 CueO—indicated that the electron transfer from the copper(I) ion as the substrate to the type I copper is performed though the hydrogen bond between Asp439 and His443, a ligand for the type I copper, and also by means of the through-space mechanism directly.

Journal

• Chemistry Letters

  Chemistry Letters 42 (9), 1102-1104, 2013-06-08

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360002219105409664
• NII Article ID: 10031194356
• NII Book ID: AA00603318
• DOI: 10.1246/cl.130422
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/42/9/1102/55642403/cl.130422.pdf
• Data Source:
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