Rational Design of a Fluorescence-amplified Aptasensor Based on Enzyme-assisted Target Recycling Strategy

DOI PDF 52 References
  • Shingo Nakao
    Division of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba
  • Motoi Oishi
    Division of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba

Search this article

Abstract

<jats:title>Abstract</jats:title> <jats:p>A fluorescence-amplified sensing system composed of a fluorophore-labeled adenosine DNA-aptamer/quencher-labeled capture DNA duplex, assistant DNA, and exonuclease III (Exo III) was designed and prepared. The newly constructed enzyme-assisted aptasensor exhibited amplification of fluorescent signal in response to adenosine (target) through an Exo III-assisted target recycling process.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 42 (10), 1122-1124, 2013-06-08

    Oxford University Press (OUP)

References(52)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top