Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming

• So Imai

• Tetsuo Cai

• Chika Yoshida

• Taisuke Tomita

• Eugene Futai

Journal

• The journal of biochemistry

  The journal of biochemistry 165 (1), 37-46, 2019-01

  Tokyo : Japanese Biochemical Society

Keywords

• Alzheimer's disease
• amyloid beta (Aβ)
• γ-secretase
• intramembrane proteolysis
• Saccharomyces cerevisiae

Details

• CRID: 1523951030604903552
• NII Article ID: 40021789427
• NII Book ID: AA00694073
• ISSN: 0021924X
• ISSN: 17562651
• DOI: 10.1093/jb/mvy081
• NDL BIB ID: 029476698
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I029476698
• Web Site: http://academic.oup.com/jb/article-pdf/165/1/37/27191232/mvy081.pdf
• Web Site: https://search.jamas.or.jp/link/ui/2019253824
• Text Lang: en
• NDL Source Classification:
  • ZR2(科学技術--生物学--生化学)
• Data Source:
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN