Design and evaluation of novel functional nanoparticles as a DNA carrier 新規機能性ナノパーティクルの設計とそのDNA医薬担体としての評価
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著者
書誌事項
- タイトル
-
Design and evaluation of novel functional nanoparticles as a DNA carrier
- タイトル別名
-
新規機能性ナノパーティクルの設計とそのDNA医薬担体としての評価
- 著者名
-
石原, 務
- 著者別名
-
イシハラ, ツトム
- 学位授与大学
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東京工業大学
- 取得学位
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博士 (工学)
- 学位授与番号
-
甲第3486号
- 学位授与年月日
-
1997-03-26
注記・抄録
博士論文
目次
- 論文目録 / (0002.jp2)
- Contents / (0004.jp2)
- ChapterI General introduction / p1 (0008.jp2)
- I-1 Gene Therapy / p1 (0008.jp2)
- I-2 Various carriers for gene delivery in vivo / p5 (0012.jp2)
- I-3 Biodegradable nanoparticles as a gene delivery carrier / p12 (0019.jp2)
- I-4 Surface modificationof nanoparticles as a gene carrier / p14 (0021.jp2)
- I-5 Objective in this study / p19 (0026.jp2)
- Chapter II Preparation of nanoparticles bearing carbohydrate on their surfaces / p26 (0034.jp2)
- II-1 Introduction / p26 (0034.jp2)
- II-2 Experimental / p26 (0034.jp2)
- II-3 Resultsand Discussion / p29 (0037.jp2)
- II-4 Conclusion / p36 (0044.jp2)
- Chapter III Preparation and characterization of nanoparticles consisting of PLL and PLA / p38 (0047.jp2)
- III-1 Introduction / p38 (0047.jp2)
- III-2 Experimental / p38 (0047.jp2)
- III-3 Results and Discussion / p41 (0050.jp2)
- III-4 Conclusion / p48 (0057.jp2)
- Chapter IV Preparation and characterization of nanoparticles which have DNA retention site and recognition site on their surfaces / p50 (0060.jp2)
- IV-1 Introduction / p50 (0060.jp2)
- IV-2 Experimental / p50 (0060.jp2)
- IV-3 Results and Discussion / p54 (0064.jp2)
- IV-4 Conclusion / p80 (0090.jp2)
- Chapter V Interaction of nanoparticles with biological components and cells / p83 (0094.jp2)
- II-1 Introduction / p83 (0094.jp2)
- II-2 Experimental / p83 (0094.jp2)
- II-3 Results and Discussion / p86 (0097.jp2)
- II-4 Conclusion / p99 (0110.jp2)
- Chapter VI Conclusion / p101 (0113.jp2)
- Abstract / (0006.jp2)