Genes
著者
書誌事項
Genes
Wiley, c1985
2nd ed
- pbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is the second edition of a widely recognized and authoritative text, written by an authority in the field. Emphasises modern topics, and reflects progress in DNA technology and focuses more on direct analysis of the genome. Preliminary chapters are presented which examine the biochemical basis for heredity as seen through the structure of DNA, making it accessible for the student with only a casual knowledge of biochemistry. Features include extensive new figures, drawings and illustrations.
目次
- DNA AS A STORE OF INFORMATION: DNA is the Genetic Material
- Genes are Carried on Chromosomes
- Mutations Change the Sequence of DNA
- The Topology of Nucleic Acids
- Isolating the Gene
- TURNING GENES INTO PROTEINS: Breaking the Genetic Code
- The Assembly Line for Protein Synthesis
- Transfer RNA: The Translational Adaptor
- The Ribosome Translation Factory
- The Messenger RNA Template
- PRODUCING THE TEMPLATE: RNA Polymerases: The Basic Transcription Apparatus
- Promoters: The Sites for Controlling Initiation
- Termination and Antitermination
- CONTROLLING GENE EXPRESSION/PROKARYOTIC: The Operon: The Lactose Paradigm
- Control Circuits: A Panopoly of Operons
- Lytic Cascades and Lysogenic Repression
- CONSTITUTION OF THE EUKARYOTIC GENOME: The Extraordinary Power of DNA Technology
- Eukaryotic Genomes: A Continuum of Sequences
- Structural Genes: As Represented in mRNA
- The Organization of Interrupted Genes
- CLUSTERS OF RELATED SEQUENCES: Structural Genes Belong to Families
- Genomes Sequestered in Organelles
- Identity and Variation in Tandem Gene Clusters
- Organization of Simple Sequence DNA
- REACHING MATURITY: RNA PROCESSING: Cutting and Trimming Stable RNA
- RNA as Catalyst: Mechanisms of RNA Splicing
- Control of RNA Processing
- THE PACKAGING OF DNA: About Genomes and Chromosomes
- Chromatin Structure: The Nucleosome
- The Nature of Active Chromatin
- PERPETUATION OF DNA: The Replicon: Unit of Replication
- The Apparatus for DNA Replication
- Systems that Safeguard DNA
- Recombination and Other Topological Manipulations of DNA
- THE DYNAMIC GENOME: DNA IN FLUX: Transposable Elements in Bacteria
- Mobile Elements in Eukaryotes
- Rearrangements and the Generation of Immune Diversity
- Engineering Changes in the Genome
- Glossary
- Index.
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