書誌事項

Steric effects in drug design

editors, M. Charton and I. Motoc ; with contributions by V. Austel ... [et al.]

(Topics in current chemistry = Fortschritte der chemischen Forschung, v. 114)

Springer-Verlag, 1983

  • : gw
  • : us

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注記

Includes bibliographies and index

内容説明・目次

内容説明

With contributions by numerous experts

目次

Features and problems of practical drug design.- Topological indices for structure-activity correlations.- The upsilon steric parameter - definition and determination.- Molecular shape descriptors.- Volume and bulk parameters.- Applications of various steric constants to quantitative analysis of structure-activity relationships.

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