Thermodynamics and control of biological free-energy transduction
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Bibliographic Information
Thermodynamics and control of biological free-energy transduction
Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1987
- : U.S.
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Note
Includes index
Description and Table of Contents
Description
This book contains a description of how quantitative notions from physics and chemistry may be applied to biological systems, in particular those involved in biological free energy transduction. Researchers in the fields of bioenergetics and biochemistry will find this volume to be an excellent, in-depth review of the subject and an invaluable source of information.
Table of Contents
Chapter 1. The basis for mosaic non-equilibrium thermodynamics. Equilibrium statistical mechanics: a basis for thermodynamics in (quantum) mechanics and statistics. Equilibrium thermodynamics. 'Classical' or 'phenomenological' non-equilibrium thermodynamics. The master equation approach to non-equilibrium systems. The Langevin approach: near-equilibrium statistical mechanics. An extension to far from equilibrium systems. Kinetics. Stability of metabolic states as the basis for thermodynamic and control properties of systems. The theory of metabolic control. The biology of some systems. Introduction to some biochemical methods. Chapter 2. The core of mosaic non-equilibrium thermodynamics. The principles. Flow-force relationships for elementary processes close to equilibrium. Force-flow relations for elementary processes far from equilibrium. Reciprocity of flow-force relations. Steady-state criteria. Towards the mosaic of elemental processes: examples. Chapter 3. Applications of mosaic non-equilibrium thermodynamics. Ion transport in bacteriorhodopsin liposomes. Mitochondrial oxidative phosphorylation. Microbial growth. Efficiency and optimisation of biological free-energy converters. Chapter 4. Control of free energy transduction . Thermodynamics and metabolic control. Control in compartmented systems. The analysis of the control of free-energy transduction in practice. Appendix A. The thermodynamics of the light-driven process. Appendix B. Statistical aspects of protonic energy coupling and metabolic chanelling. References. Subject Index.
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