Genome analysis : a practical approach

Author(s)

• Davies, Kay

Bibliographic Information

Genome analysis : a practical approach

edited by K.E. Davies

（The practical approach series）

IRL Press, 1988

• : hard
• : pbk.

Note

Includes bibliographies and index

Description and Table of Contents

Volume

: hard ISBN 9781852211097

Description

Includes : Techniques for mammalian genome transfer; genome mapping by restriction fingerprinting; pulsed field gel electrophoresis and the technology of large DNA molecules; chromosome jumping; the polymerase chain reaction; DNA fingerprinting; mapping complex genetic traits in humans This book is intended for postgraduates and researchers in molecular biology, biochemistry.

Table of Contents

• Abbreviations
• P.N. Goodfellow, C.A. Pritchard, & G.S. Banting: Techniques for mammalian genome transfer
• A. Coulson & J. Sulston: Genome mapping by restriction fingerprinting
• C.L. Smith, S.R. Klco, & C.R. Cantor: Pulsed-field gel electrophoresis and the technology of large DNA molecules
• F.S. Collins: Chromosome jumping
• R.M. Myers, V.C. Sheffield, & D.R. Cox: Detection of single base changes in DNA: ribonuclease cleavage and denaturing gradient gel electrophoresis
• R.K. Saiki, U.B. Gyllensten, & H.A. Erlich: The polymerase chain reaction
• R.A. Wells: DNA fingerprinting
• E.S. Lander: Mapping complex genetic traits in humans
• Index

Volume

: pbk. ISBN 9781852211103

Description

Methodologies used to analyse the genomes of prokaryotes and eukaryotes are advancing very rapidly as it has been realized that there is a resolution gap between what can be viewed under the microscope and what molecular techniques can resolve. This book presents current, successful strategies for construction of physical maps to identify and analyse the arrangement and function of genes. These techniques, which are applicable to a range of organisms, are being used to move from linked markers to candidate genes in several human monogenic disorders. They are presented in a way that should enable any research or diagnostic laboratory to apply them to their particular systems. Also included are descriptions of new probes and approaches for the localization of human disorders whose analysis has so far eluded the molecular geneticist.

Table of Contents

• Goodfellow: Techniques for mammalian genome transfer
• Coulson: Genome mapping by restriction fingerprinting
• Smith: Pulsed-field gel electrophoresis and the technology of large DNA molecules
• Collins: Chromosome jumping
• Myers: Detection of single base changes in DNA
• Saiki: The polymerase chain reaction
• Wells: DNA fingerprinting
• Lander: Mapping complex genetic traits in humans

by "Nielsen BookData"

Details

• NCID: BA04889185
• ISBN:
  • 1852211091
  • 1852211105
• LCCN: 88023023
• Country Code: uk
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Oxford ; Washington, DC
• Pages/Volumes: xiv, 192 p.
• Size: 24 cm
• Classification:
  • NLM : QH445.2
  • LCC : QH445.2
  • DC19 : 575.1/2
• Subject Headings:
  • LCSH : Chromosome mapping -- Technique
  • MESH : Chromosome Mapping
• Parent Bibliography ID:
  • BA00227768