Elements of molecular neurobiology

書誌事項

Elements of molecular neurobiology

C.U.M. Smith

(A Wiley medical publication)

J. Wiley, c1989

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注記

Bibliography: p. 501-514

Includes index

内容説明・目次

内容説明

The 1980s have seen spectacular advances in our understanding of the molecular bases of neurobiology. Biological membranes, channel proteins, cytoskeletal elements, and neuroactive peptides have all been illuminated by the molecular approach. The operation of synapses can be seen to be far more subtle and complex than has previously been imagined, and the development of the brain and physical basis of memory have both been illuminated by this new understanding. In addition, some of the ways in which the brain may go wrong can be traced to malfunction at the molecular level. This study attemps a synthesis of this new knowledge, to provide an indication of how an understanding at the molecular level can help towards a theory of the brain in health and disease. The text will be of benefit to undergraduate students of biochemistry, medical science, pharmacy, pharmacology and general biology.

目次

  • The conformation of informational macromolecules
  • information processing in cells
  • molecular evolution
  • manipulating biomolecules
  • biomembranes
  • g-coupled receptors
  • pumps
  • ligand-gated channels
  • voltage-gated channels
  • resting potentials and cable conduction
  • sensory transduction
  • the action potential
  • the neuron as a secretory cell
  • neurotransmitters and neuromodulators
  • the subsynaptic membrane
  • epigenetics of the brain
  • memory
  • five pathologies.

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