Potassium channels : basic function and therapeutic aspects : proceedings of the 29th Annual A.N. Richards Symposium held at Valley Forge, Pennsylvania, May 16-17, 1988
著者
書誌事項
Potassium channels : basic function and therapeutic aspects : proceedings of the 29th Annual A.N. Richards Symposium held at Valley Forge, Pennsylvania, May 16-17, 1988
(Progress in clinical and biological research, v. 334)
Wiley-Liss, c1990
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注記
Includes bibliographical references (p. 335-338) and index
内容説明・目次
内容説明
Covering recent research into the role of potassium channel activity in normal cellular function and in disease processes, this volume reviews mechanisms of potassium channel block and activation with studies on nerve, cardiac and vascular smooth muscle. Changes in potassium channel function in hypertension, ischemic heart disease, arrhythmia production and myocardial hypertrophy are discussed along with explorations into the modulatory role of potassium channels in learning and mitogenesis. The book considers techniques such as the single cell voltage clamp; single channel recordings; channel isolation and purification; and tracer flux measurements. Established experts have incorporated data from electrophysiologic, biochemical, radioflux and molecular biologic experiments, addressing normal and pathophysiologic conditions.
目次
- PART I: Overview
- PART II: Potassium Channels in the Heart
- PART III: Potassium Channels in Smooth Muscle
- PART IV: Potassium Channels in Nerve and Other Membranes
- PART V: Modulation of Potassium Channel Activity by Drugs and Hormones.
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