Immunology

Author(s)

Bibliographic Information

Immunology

Jan Klein

Blackwell Scientific Publications, 1990

  • : pbk

Available at  / 47 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Volume

ISBN 9780865421165

Description

This textbook contains an account of self/non self discrimination in other invertebrate and vertebrate organisms. Klein demonstrates how the intricate molecular and cellular mechanisms of defence are fashioned by evolution as answers to a variety of biological problems of survival. He goes on to describe our understanding of lymphoid organs, T and B cells, immunoglobulins, lymphokines, histocompatibility, tolerance and the concepts and experiments that define modern immunology. Up-to-date and aiming to do justice to the new molecular understanding of the subject this book redefines the contours of a discipline that increasingly occupies centre stage in modern life science. It emphasizes current trends in immunological research and describes the organization of the immune system, the components of the immune response and the immune system and disease.

Table of Contents

  • Introduction to vertebrate immunity
  • blood cells and their origin
  • lymphocytes and the rest
  • lymphoid organs
  • the t-cell receptor
  • immunoglobulins and their receptors
  • the major histocompatibility complex
  • complement
  • lymphokines and their receptors
  • mediators and messengers
  • antigens and other lymphocyte-activating substances
  • antigen antibody interactions
  • defence reactions mediated by phagocytes
  • T lymphocyte responses
  • B lymphocyte responses
  • systemic and regional immune responses
  • regulation of the immune response
  • immunological tolerance
  • defence against pathogens and parasites
  • defence against tumours
  • allergies and other antibody mediated hypersensitivities
  • delayed type hypersensitivity
  • allograft reaction
  • autoimmunity and autoimmune diseases
  • immunodeficiency diseases
  • immunoprophylaxis.
Volume

: pbk ISBN 9780865421516

Description

Beginning with an account of self/non-self discrimination in othe invertebrate and vertebrate organisms, Klein demonstrates how the intricate molecular and cellular mechanisms of defence are fashioned by evolution as answers to a variety of problems of survival. He goes on to describe in detail the lymphoid organisms, T and B cells, immunoglobulins, lymphokines, histocompatibility and tolerance. This book won the Glaxo Prize for Medical Writing and Illustration 1990.

Table of Contents

  • Introduction to vertebrate immunity
  • Blood cells and their origin
  • Lymphocytes and the rest
  • Lymphoid organs
  • The T-cell receptor
  • Immunoglobulins and their receptors
  • The major histocompatibility complex
  • Complement
  • Lymphokines and their receptors
  • Mediators and messengers
  • Antigens and other lymphocyte-activating substances
  • Antigen-antibody interactions
  • Defence reactions mediated by phagocytes
  • T lymphocyte responses
  • B lymphocyte responses
  • Systemic and regional immune responses
  • Regulation of the immune response
  • Immunological tolerance
  • Defence against pathogens and parasites
  • Defence agains tumours
  • Allergies and other antibody-mediated hypersensitivities
  • Delayed-type hypersensitivity
  • Allograft reaction
  • Autoimmunity and autoimmune diseases
  • Immunodeficiency diseases
  • Immunoprophylaxis.

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