Skin pharmacology and toxicology : recent advances
著者
書誌事項
Skin pharmacology and toxicology : recent advances
(NATO ASI series, ser. A . Life sciences ; v. 181)
Plenum Press, c1990
大学図書館所蔵 全8件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
"Proceedings of a NATO Advanced Study Institute on Recent Advances in Skin Pharmacology and Toxicology, held April 9-19, 1989, in Riva del Garda, Italy"--T.p. verso
"Published in cooperation with NATO Scientific Affairs Division."
Includes bibliographical references and index
内容説明・目次
内容説明
Major skin diseases, including acne, psoriasis and eczcma, affect the majority of the population at some time in their lives. In general, these diseases are physically and psychologically disfiguring for the sufferers; furthermore, by their very chronic nature skin diseases, unlike most other disease processes, present both acute and chronic therapy problems. In addition, the chronic nature of these diseases can present certain economic problems. Firstly, chronic therapy is becoming increasingly expensive and secondly, patients adhering to a strict treatment regimen will frequently be absent from their gainful employment for either medical consultation or treatment. Given that in all NATO countries the average age of the population is continually increasing, these chronic skin diseases will increase in importance in the coming years. Furthermore, as the average population age increases, additional disease processes such as skin photodamage and carcinogenicity risk becoming major areas of therapeutic concern. This book reviews in detail the major scientific areas of interest for research and clinical scientists working in skin pharmacology and toxicology. The basic principles relating to an understanding of how drugs and chemicals may influence either the skin or the body as a whole are discussed in detail by recognized international scientific experts.
目次
- Dermatological Drug Development - A Review of some Important Issues.- Carbohydrate, Protein and Lipid Metabolism in the Skin
- Biochemical and Molecular Aspects.- Hormone Receptors in the Skin.- Skin Permeability and Models of Percutaneous Absorption.- Skin as a Portal of Entry for Systemic Effect: Xenobiotic Metabolism85 D.R. Bickers.- Animal Models Used in Cutaneous Pharmacology.- Hyperplastic Transformation: the Response of the Skin to Irritation and Injury.- The Evaluation of Cutaneous Toxicity: Past and Future.- In Vitro Biochemical Markers of Skin Toxicity.- The Use of Cultured Human Keratinocytes as a Model System for Skin Pharmacology and Toxicology.- Pro-Inflammatory Mediators and Human Skin Disease.- Studies of Photoaging.- Photosensitization Chemically Induced: Mechanisms and Clinical Aspects.- Molecular and Cellular Mechanisms of Multistage Carcinogenesis
- Role of Oncogenes and Intercellular Communication.- Contact and Atopic Dermatitis.- In Vitro Expanded Human Keratinocytes: Clinical and Biological Experiences.- A Comparative Evaluation of Sun Protective Properties of a Shea Butter by Reflectance Spectroscopy, Laser Doppler Flowmetry and Visual Scoring.- A Computer System for Contact Dermatitis.- Nuclear Aberrations in Anagen Hair Follicle Cells
- a Novel in Vivo Assay for the Detection of Genotoxic Agents.- A New Evaluation Method of Skin Plastoelasticity.- An Interspecies Comparison of Skin Structure (Hair Follicle Area as Determined by a Novel Technique) and Skin Permeability.- Chemical-Induced Differentiation of Cultured Human Keratinocytes as Measured by Cell Size Distribution.- Contributors.
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