Oligodeoxynucleotides : antisense inhibitors of gene expression
Author(s)
Bibliographic Information
Oligodeoxynucleotides : antisense inhibitors of gene expression
(Topics in molecular and structural biology, v. 12)
Macmillan Press, 1989
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Note
Includes bibliographical references nd index
Description and Table of Contents
Description
The recent work on the natural occurrence of antisense RNA and subsequent use of antisense constructs to manipulate gene expression has been of enormous value to molecular biologists and it provides the bulwark behind the endeavours discussed in this publication of the state of the field.
Table of Contents
- Strategies and realities, J.S.Cohen
- synthesis of oligonucleotides and oligonucleotide analogues, M.H.Caruthers
- oligodeoxynucleotides covalently linked to intercalating and reactive substances - synthesis, characterization and physicochemical studies, Nguyen Thanh Thuong et al
- inhibition of gene expression by oligonucleotides, J.Goodchild
- non-ionic antisense oligonucleotides, P.S.Miller
- phosphorothioate oligodeoxynucleotide analogues, C.A.Stein and J.S.Cohen
- oligodeoxynucleotide analogues, B.Rayner et al
- control of gene expression by oligodeoxynucleotides covalently linked to intercalating agents and nucleic acid-cleaving reagents, C.Helene and J.J.Toulme
- oligonucleotides linked to reactive groups, D.G.Knorre et al
- oligonucleotide recognition of double helical DNA by triple helix formation, P.B.Dervan
- antisense oligodeoxynucleotides as a tool for studying cell regulation - mechanisms of uptake and application to the study of oncogene function, L.M.Neckers
- pharmaceutical considerations, G.Zon.
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