DNA methylation and gene regulation : proceedings of a Royal Society discussion meeting held on 1 and 2 February 1989

著者

書誌事項

DNA methylation and gene regulation : proceedings of a Royal Society discussion meeting held on 1 and 2 February 1989

organized and edited by R. Holliday, Marilyn Monk and J. E. Pugh

Royal Society, 1990

タイトル別名

Philosophical Transactions of the Royal Society of London

大学図書館所蔵 件 / 全13件

この図書・雑誌をさがす

注記

"First published in Philosophical Transactions of the Royal Society of London, series B, volume 326 (no. 1234), pages 177-338." -- t.p. verso

内容説明・目次

内容説明

This book comprises papers given at a Royal Society Discussion Meeting held in February 1989. The papers in this volume review and assess the significance of the advances that have been made, by using a variety of experimentatal systems, concerning the possible importance of DNA methylation in controlling the activity of genes during development. Contributions range from the cloning and sequencing of the major mammalian methyl transferase to the control of chromosome activity, which underlies the process of genomic imprinting. Papers review the use of DNA methylases in "in vitro" methylation, the methylation of maize transposable elements (and the correlation of this with activity), and DNA methylation patterns, and DNA methylation and specific protein-DNA interactions. Three articles discuss CpG islands that show tissue-specific demethylation of genes in animal cells. There are also articles on the probability that DNA methylation and late replication aid cell memory, relating DNA methylation during mouse embryotic development to X-chromosomes by DNA methylation and DNA methylation and epigenetic inheritance.

目次

  • DNA methylation - evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes, T.H.Bestor
  • eukaryotic DNA methylases and their use for "in vitro" methylation, R.L.P.Adams et al
  • a nuclear protein that binds preferentially to methylated DNA "in vitro" may play a role in the inaccessibility of methylated CpGs in mammalian nuclei, R.Meehan et al
  • CpG islands in genes showing tissue-specific expression, Yvonne H.Edwards
  • DNA methylation of maize transposable elements is correlated with activity, Elizabeth S.Dennis and R.I.S.Brettell
  • tissue specific expression of avian vitellagenin gene is correlated with DNA hypomethylation and "in vivo" specific protein-DNA interactions, J.P.Lost et al
  • demethylation of genes in animal cells, D.Frank et al
  • the significance of DNA methylation patterns - promoter inhibition by sequence-specific methylation is one functional consequence, W.Doerfler
  • DNA methylation and specific protein-DNA interactions, P.L.Molloy and F.Watt
  • methylation and expression of the "Myo D1" determination gene, P.A.Jones et al
  • DNA methylation and late replication probably aid cell memory, and type I DNA reeling could aid chromosome folding enchance function, A.D.Riggs
  • changes in DNA methylation during mouse embryotic development in relation to X-chromosome activity and imprinting, Marilyn Monk
  • developmental consequences of imprinting of parental chromosomes by DNA methylation, M.A.Surani
  • DNA methylation and epigenetic inheritance, R.Holliday.

「Nielsen BookData」 より

詳細情報

ページトップへ