Eosinophils, allergy and asthma

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書誌事項

Eosinophils, allergy and asthma

edited by A.B. Kay

Blackwell Scientific Pub., 1990

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注記

A summary of a 2-day meeting of 'Eosinophils, Allergy and Asthma' which was held at the Royal Society of Medicine, London, in December 1988

内容説明・目次

内容説明

The eosinophil is a type of white blood cell which plays a crucial role in the immunological defence mechanisms of the human body. Professor Kay has brought together an internationally respected group of doctors and scientists to produce a research level monograph which describes the recent advances in understanding which have placed the eosinophil at the centre of numerous pathophysiological mechanisms underlying allergy and asthma. This up to date, state of the art treatise includes chapters on the molecular biology and immunology of the eosinophil, the interactions of eosinophils with other blood elements and with the major immunological mediators in the body such as interleukin-5, platelet activating factor. There is also detailed coverage of the very latest advances in the anti-allergic drug research which promise to revolutionise the therapy of allergy and asthma.

目次

  • List of contributors
  • Preface
  • Structural analysis of amino acid and cDNA nucleotide sequence of eosinophil major based protein
  • Immunoglobulin receptors on eosinophil leucocytes
  • Interleukin-5
  • Eosinophil chemotactic factors in asthma and allergy
  • Interactions between monocytes, macrophages and eosinophils
  • Interactions between PAF, cytokines, the CD 11/18 complex and eosinophil adherence reactions in vitro
  • IgE-dependent eosinophil effector mechanisms
  • Eosinophils and pulmonary hyperresponsiveness in the rat
  • Potential involvement of interleukin-5 and platelet-activating factor in eosinophil recruitment in the rat
  • The role of neutophils and eosinophils in a model of asthma in the guinea pig
  • Eosinophil granule proteins in bronchial asthma
  • Mononuclear cell-derived eosinophil-activating factors
  • Inhibition of allergen-induced cutaneous eosinophilia
  • Eosinophils, T-lymphoeytes and late-phase skin reactions
  • Inhibition of PAF-induced eosinophilia by AH 21-132
  • Eosinophils and bronchial hyperresponsiveness in bronchial astma
  • Pharmacology of eosinophils
  • Index

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