Effects of therapy on biology and kinetics of the residual tumor : proceedings of an International Symposium on the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, held in Vancouver, British Columbia, Canada, February 15-18, 1989

著者

書誌事項

Effects of therapy on biology and kinetics of the residual tumor : proceedings of an International Symposium on the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, held in Vancouver, British Columbia, Canada, February 15-18, 1989

editors, Joseph Ragaz ... [et al.]

（Progress in clinical and biological research, v. 354）

Wiley-Liss, c1990

  • pt. A
  • pt. B

大学図書館所蔵 件 / 全4件

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注記

Includes bibliographical references

Includes index

収録内容

  • pt. A. Pre-clinical aspects
  • pt. B. Clinical aspects

内容説明・目次

巻冊次

pt. A ISBN 9780471568292

内容説明

This volume examines the effectiveness of different cancer treatment modalities as applied under a range of individual conditions. It specifically deals with kinetics, growth factors, metastases and immunity, and genetic regulation.

目次

  • Partial table of contents:
  • Review of the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, Part I (J. Ragaz)
  • KINETICS
  • Effects of the Initial Chemotherapy on Subsequent Therapy (L. Simpson-Herren & P. Noker)
  • Proliferative and Vascular Responses to Cytoreduction in Solid Tumor Models (P. Braunschweiger)
  • KINETICS AND TREATMENT DESIGN
  • Tumor Differences, Drug Differences, Treatment Design Differences, and Effects on Therapeutic Outcome (Degree and Duration of Therapeutic Response) (H. Skipper)
  • Genetic and Kinetic Factors in the Drug Resistance of Micrometastatic Disease (J. Goldie)
  • Biology of Residual Breast Cancer After Therapy: A Kinetic Interpretation (L. Norton)
  • GROWTH FACTORS
  • Growth Control of Normal and Malignant Breast Epithelium (M. Lippman & R. Dickson)
  • Inhibitors of Bombesin-Stimulated Intracellular Signals: Interruption of an Autocrine Pathway as a Therapeutic Strategy in Small Cell Lung Carcinoma (E. Sausville, et al.)
  • GENETIC REGULATION OF TUMOR GROWTH
  • Growth Control in Leukemia (A. Eaves & C. Eaves)
  • METASTASES AND IMMUNITY
  • Macrophages, Metastasis and Immunity (N. Phillips)
  • Development of Myelorestorative and Immunotherapeutic Properties of Cytokines (J. Talmadge, et al.)
  • MICROENVIRONMENT, DIFFERENTIATION, AND CHEMOPREVENTION
  • Cellular Maturation and Oncogene Expression During Drug-Induced Differentiation In Vitro: A Brief Review (J. Biedler, et al.)
  • Leaky Tumor Vessels: Consequences for Tumor Stroma Generation and for Solid Tumor Therapy (H. Dvorak)
  • Embryonic Mechanisms for Abrogating the Malignancy of Cancer Cells (R. Parchment, et al.)
  • SUMMARY
  • Index.
巻冊次

pt. B ISBN 9780471568308

内容説明

The two volumes of this work examine the effectiveness of different cancer treatment modalities as applied under a range of individual conditions and, further, discusses the behaviour of residual tumours that survive such treatments. Serving as both a source of information and a guide to future research, this work deals with pre-clinical tumours, covering the short and long-term consequences of various techniques on both the host patient and the carcinoma itself. Among the many pre-clinical issues discussed in Part A are kinetics, growth factors, metastases and immunity, and genetic regulation. Part B treats clinical aspects such as biological response modifiers, radiobiology, autologous bone marrow transplantation and more.

目次

  • Partial table of contents:
  • BIOLOGICAL RESPONSE MODIFIERS
  • Tumor Treatment and Cytokines (J. Schrader, et al.)
  • Towards Improved Cancer Therapy Using Subcutaneously Administered Hemopoietic Colony Stimulating Factors (G. Morstyn, et al.)
  • Mechanisms of Action of Interferon (H. Ozer)
  • RADIOBIOLOGY
  • The Growth Kinetics of Clonogenic Tumor Cells That Survive Radiation Therapy (R. Kallman & C. Hughes)
  • Microenvironmental Changes in Irradiated Tumors (S. Rockwell & C. Hughes)
  • CLINICAL ASPECTS OF THERAPY--INTEGRATION OF DOSE INTENSITY KINETICS AND BIOLOGY WITH TREATMENT PLANNING
  • Modeling the Effect of Chemotherapy Intensity (C. Coppin, et al.)
  • Comments on Kinetics and Biology of the Residual Cancer, and on Relevant Therapeutic Strategies Based on These Phenomena (J. Ragaz)
  • AUTOLOGOUS BONE MARROW TRANSPLANTATION
  • Autologous Bone Marrow Transplantation for Hematologic Cancer (G. Phillips)
  • Use of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Support Intensive Chemotherapy (H.-G
  • Klingemann)
  • CONSEQUENCES OF THERAPY
  • Induction of Secondary Neoplasms by the Treatment of Malignant Disease: Lessons from Hodgkin's Disease (J. Connors)
  • Overview of Adjuvant Radiotherapy for Breast Cancer (J. Cuzick)
  • Chemotherapy Schedules: Impact on Treatment Outcomes and Quality of Life (M. Tattersall)
  • SUMMARY
  • Index.

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