Disorders of movement : clinical, pharmacological and physiological aspects

書誌事項

Disorders of movement : clinical, pharmacological and physiological aspects

edited by N. P. Quinn, P. G. Jenner

Academic Press, c1989

大学図書館所蔵 件 / 6

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内容説明・目次

内容説明

Professor David Marsden is a world authority on movement disorders. His past and present students and co-workers have produced this compilation of a wealth of knowledge, covering a wide range of motor disturbances, as a tribute to him.

目次

  • Part 1 Parkinson's disease: is there a Parkinson's disease?
  • organization of the basal ganglia
  • the pathology of Parkinson's disease
  • the pathophysiology of Parkinson's disease
  • models of cognitive dysfunction in Parkinson's disease
  • biochemistry of neurotransmitters in Parkinson's disease
  • the neurochemistry of Parkinson's disease as revealed by PET scanning
  • sleep and Parkinson's disease
  • different therapeutic approaches to complicated Parkinson's disease
  • the anti-Parkinsonian effects of transdermal (+)-PHONO -MPTP and its relevance to Parkinson's disease
  • the role of dopamine in the selectivity of the neurotoxin MPTP for nigrostriatal dopamine neurons
  • effects of dopamine D-1 and D-2 receptor stimulation in MPTP monkeys
  • chronic infusions of dopamine agonists in animals
  • delivery of (+)-4-propyl-9-hydroxy-naphthoxazine [(+)-PHNO] by a novel orally administered osmotic tablet - behavioural effect in animal models of Parkinson's disease
  • studies towards neural transplantation in Parkinson's disease - dystonia - the pathophysiology of dystonia
  • pathophysiology of cranial dystonia - a review
  • positron emission tomographic investigations of dystonia
  • blepharospasm - clinical aspects of their therapeutic considerations
  • the treatment of spasmodic torticollis
  • surgical treatment of spasmodic torticollis
  • drug treatment of dystonia
  • dopa-responsive dystonia - 20 years into the levodopa era
  • the clinical use of botulinium toxin
  • dystonia
  • where next?. Part 2 Neuroleptic-induced movement disorders: neuroleptic-induced movement disorders
  • the consequences of chronic exposure to neuroleptics in the rat
  • experimental models of acute dystonia. Part 3 Other movement disorders: degenerative ataxic disorders
  • the physiology of myoclonus in man
  • experimental models of myoclonus
  • the bio-chemistry of Huntington's chorea
  • classification of tremor
  • orthostatic tremor
  • long-latency reflexes
  • cortical stimulation in man. Part 4 Concluding Remarks: movement disorders
  • the problem of definition.

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