Heat shock and development
著者
書誌事項
Heat shock and development
（Results and problems in cell differentiation, 17）
Springer-Verlag, c1991
- : gw
- : us
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注記
Includes bibliographical references
内容説明・目次
内容説明
The possible roles of heat shock proteins in normal development in animals, plants and model systems and the effects of elevated temperature on developmental programs are comprehensively treated. All relevant aspects of heat shock genes in normal and abnormal development are discussed, as are the major biological systems currently used to study the developmental biology of heat shock genes. Heat is a medically significant teratogen in humans and animals. The heat shock response itself is developmentally regulated and is likely to be protective in the developing embryo. In addition to roles in stress responses, heat shock genes are differentially expressed during normal development in germ tissues and in the specialized cell types of somatic tissues such as the mammalian brain. Heat shock genes are regulated during the cell cycle and heat shock promoters can be used in ectopic expression systems to study the functions of particular genes during development.
目次
I Heat Shock-Induced Developmental Abnormalties.- 1 Heat Shock Effects in Snail Development.- 2 Environmentally Induced Development Defects in Drosophila.- 3 The Use of Heat-Shock-Induced Ectopic Expression to Examine the Functions of Genes Regulating Development.- 4 Thermotolerance and Heat Shock Response During Early Development of the Mammalian Embryo.- 5 Strain Differences in Expression of the Murine Heat Shock Response: Implications for Abnormal Neural Development.- II Cell-Specific and Developmental Control of Hsp Synthesis.- 6 The Expression of Heat Shock Protein and Cognate Genes During Plant Development.- 7 Expression of Heat Shock Proteins During Development in Drosophila.- 8 Regulation of Heat Shock Gene Expression During Xenopus Development.- 9 Heat Shock Gene Expression During Mammalian Gametogenesis and Early Embryogenesis.- 10 Heat Shock Protein Synthesis in Preimplantation Mouse Embryo and Embryonal Carcinoma Cells.- 11 Transcriptional Regulation of Human Hsp70 Genes: Relationship Between Cell Growth, Differentiation, Virus Infection, and the Stress Response.- 12 Transforming Growth Factor-? Regulates Basal Expression of the hsp70 Gene Family in Cultured Chicken Embryo Cells.- 13 Cell Growth, Cytoskeleton, and Heat Shock Proteins.- 14 Expression of Heat Shock Genes (hsp70) in the Mammalian Nervous System.
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