Methods of hormone radioimmunoassay

著者

• Jaffe, Bernard M.
• Behrman, Harold R.

書誌事項

Methods of hormone radioimmunoassay

edited by Bernard M. Jaffe, Harold R. Behrman

Academic Press, 1979

2nd ed

注記

Includes bibliographies and index

内容説明・目次

内容説明

Methods of Hormone Radioimmunoassay, Second Edition is a compilation of radioimmunoassay techniques for the quantification of hormones. Various kinds of hormones are considered, namely: intracellular messengers; hypothalamic and pineal hormones; pituitary hormones; thyroid and parathyroid hormones; renal hormones; hormones of the gastrointestinal tract; pancreatic hormones; steroid hormones; uterine and placental hormones; vasoactive peptide hormones; and growth factors. The corresponding method of radioimmunoassay for each hormone is described. This book is comprised of 49 chapters and begins with a discussion on the radioimmunoassay of cyclic adenosine-3',5-monophosphate (cAMP) and cyclic guanosine-3,5'-monophosphate (cGMP), together with problems related to measuring both compounds. The reader is then introduced to prostaglandins and prostaglandin metabolites, thyrotropin-releasing hormone, and gonadotropin-releasing hormone. Pituitaty gonadotropins, prolactin, and thyrotropin are also discussed. The remaining chapters deal with hormones of the gastrointestinal tract, pancreatic hormones, steroid hormones, and growth factors. This monograph is intended for both clinicians and investigators interested in methods of hormone radioimmunoassay.

目次

List of Contributors Preface Preface to First Edition Intracellular Messengers 1 Cyclic AMP and Cyclic GMP I. Introduction II. Method of Radioimmunoassay III. Problems Related to Measuring cAMP and cGMP References 2 Prostaglandins and Prostaglandin Metabolites I. Introduction II. Method of Radioimmunoassay III. Evaluation of the Radioimmunoassay IV. Prostaglandin Metabolites References Hypothalamic and Pineal Hormones 3 Thyrotropin-Releasing Hormone I. Introduction II. Method of Radioimmunoassay III. Assay and Inactivation of TRH in Biologic Fluids and Tissue IV. Conclusions References 4 Gonadotropin-Releasing Hormone I. Introduction II. Radioimmunoassay III. Summary References 5 Somatostatin I. Introduction II. Materials III. Methods IV. Characteristics of the SRIF Radioimmunoassay V. Measurement of SRIF References 6 Melatonin I. Introduction II. Methods of Radioimmunoassay III. Radioimmunoassay Technique IV. Applications and Importance of Melatonin Radioimmunoassay V. Radioiodinated Melatonin Analog References 7 Substance P I. Introduction II. Assay Techniques III. Some Characteristics and Results of the Assay References 8 Neurotensin and Related Substances I. Introduction II. General Considerations for Intermediate-Sized Peptides III. Specific Considerations for Neurotensin IV. Methods V. Conclusion References Pituitary Hormones 9 Pituitary Gonadotropins I. Introduction II. Procedural Details of Radioimmunoassay III. Application to Measurement of Tissue Receptor-Bound LH IV Normal Values for Human LH and FSH V. Conclusions References 10 Prolactin I. Introduction II. Bioassays III. Radioimmunoassays IV. Radioimmunoassay Method V. Hormonal Heterogeneity VI. Clinical Results References 11 Growth Hormone I. Introduction II. Preparation of Buffers and Columns for hGH Assay III. Technique of Radioimmunoassay IV. Cross-Reactivity with Other Hormones V. Measurements of the Hormone in Blood VI. Measurements of the Hormone in Tissue and Urine References 12 Adrenocorticotropic Hormone (ACTH) I. Introduction II. Methods of Radioimmunoassay III. Problems IV. Other Radioimmunoassays V Recent Developments References 13 Melanocyte-Stimulating Hormones (MSH's) and Lipotropic Hormones (LPH's) I. Introduction II. Methods of Radioimmunoassay III. Problems References 14 Thyrotropin I. Introduction II. Method of Radioimmunoassay III. Other Immunoassays References 15 Oxytocin I. Introduction and History II. Methods of Radioimmunoassay III. Sensitivity, Cross-Reactivity, and Validation IV Oxytocin in Plasma V. Discussion References 16 Vasopressin I. Introduction and History II. Methods of Radioimmunoassay III. Sensitivity, Cross-Reactivity, and Validation IV. Vasopressin in Plasma V. Comparison with Other Assays References Thyroid and Parathyroid Hormones 17 Human Calcitonin: Application of Affinity Chromatography I. Introduction II. Method of Radioimmunoassay III. Interpretation of Radioimmunoassay Data IV. Concentrations of Calcitonin in Human Serum and Urine V. Affinity Chromatography References 18 Thyroxine and Triiodothyronine I. Introduction II. Principles of T3 and T4 Radioimmunoassay III. Rapid Simultaneous Radioimmunoassay for T3 and T4 in Unextracted Serum IV. Comparison of Various T3 and T4 Radioimmunoassay Techniques and Results V. Physiological Considerations VI. Screening for Congenital Hypothyroidism VII. Summary and Conclusions References 19 Parathyroid Hormone I. Introduction II. Methodology III. Interpretation of Radioimmunoassay Data References Renal Hormones 20 Erythropoietin I. Introduction II. Erythropoietin Sources III. Radioimmunoassay IV. Measurements of Erythropoietin in Blood V Final Comments References 21 Vitamin D Metabolites I. Introduction II. 25-OHD Assays III. 1,25-(OH)2D Assays IV. 24,25-(OH)2D Assays V. Summary References Addendum Hormones of the Gastrointestinal Tract 22 Gastrin and Related Peptides I. Introduction II. Methods of Radioimmunoassay III. Evaluation of Radioimmunoassay Data IV. Measurement of Gastrin Tetrapeptide References 23 Secretin I. Introduction II. Methods of Radioimmunoassay III. Evaluation and Validation of the Method References 24 Cholecystokinin-Pancreozymin I. Introduction II. Methods III. Evaluation of the Radioimmunoassay IV. Results Obtained with Cholecystokinin Radioimmunoassays References 25 Serotonin I. Introduction II. Methods of Radioimmunoassay III. Validation and Characterization of the Assay IV. Summary References 26 Gastric Inhibitory Polypeptide I. Introduction II. Method of Radioimmunoassay III. Evaluation of Radioimmunoassay Data References 27 Vasoactive Intestinal Peptide I. Introduction II. Method of Radioimmunoassay III. Assay Characteristics IV. Conclusion References 28 Motilin I. Introduction II. Method of Radioimmunoassay III. Evaluation of the Radioimmunoassay IV Affinity Chromatography References 29 Bombesin-like Peptides I. Introduction II. Method of Radioimmunoassay III. Bombesin-like Material in Tissues References 30 Bile Acids I. Introduction II. Methods of Radioimmunoassay III. Vilidation of Assay IV Normal Values and Concentrations of the Individual Bile Acids in Serum in Various States of Hepatobiliary Disease References Pancreatic Hormones 31 Insulin, Proinsulin, and C-Peptide I. Introduction II. Methods of Radioimmunoassay III. Verification of Assay Data IV Problems Related to the Measurement of Insulin and Proinsulin V. Other Radioimmunoassays Available VI. Radioimmunoassay for Human C-Peptide References 32 Glucagon I. Introduction II. Special Problems Encountered in the Measurement of Plasma Glucagon by Radioimmunoassay III. Methods of Radioimmunoassay References 33 Human Pancreatic Polypeptide (HPP) and Bovine Pancreatic Polypeptide (BPP) I. Introduction II. Methods of Radioimmunoassay III. Homologous and Heterologous Assays IV. Alternate Methods References Steroid Hormones 34 Plasma Estradiol, Estrone, Estriol, and Urinary Estriol Glucuronide I. Plasma Estradiol, Estrone, and Estriol II. Urinary Estriol Glucuronide References 35 Progesterone and 20a-Dihydroprogesterone I. Introduction II. Methods of Radioimmunoassay III. Sensitivity and Precision References 36 Androgens: Testosterone and Dihydrotestosterone I. Introduction II. Method of Radioimmunoassay III. Validation of Assay IV. Normal Values V. Other Androgens-Ahdrostenedione References 37 Radioiodinated Steroid Hormones-General Principles I. Introduction II. Advantages and Disadvantages of Radioiodinated Steroids III. Preparation of the Steroid Analogs for Radioiodination IV. Radioiodination of Steroid Hormones V. Purification of Radioiodinated Steroid Hormones VI. Development and/or Adaptation of Radioimmunoassay Procedures VII. Summary References 38 Mineralocorticoids: Aldosterone, Deoxycorticosterone, 18-Hydroxydeoxycorticosterone, and 18-Hydroxycorticosterone I. Introduction II. Methods of Radioimmunoassay III. Evaluation of the Radioimmunoassay IV. Problems Related to Measuring Mineralocorticoids V. Other Radioimmunoassay Methods VI. New Developments References 39 Glucocorticoids: Cortisol, Cortisone, Corticosterone, Compound S, and Their Metabolites I. Introduction II. Methods of Radioimmunoassay III. Evaluation of Radioimmunoassay Data IV. Other Uses for Cortisol and Corticosterone Antibody V. General Discussion References 40 Arthropod Molting Hormones I. Introduction II. Quantification of Ecdysteroids III. Comparison of Available Radioimmunoassays for Ecdysteroids IV. Protocol V. Dual Antisera Determinations References Uterine and Placental Hormones 41 Specific Human Chorionic Gonadotropin Assay I. Introduction II. Method of Radioimmunoassay References 42 Radioimmuno- and Radioreceptor Assays of Placental Lactogens I. Introduction II. Radioimmunoassay III. Radioreceptor Assays for hPL IV. Applications of Radioimmunoassay and Radioreceptor Assays V. Summary References 43 Radioimmunoassay of Human Chorionic Thyrotropin I. Introduction II. Technique of hCT Radioimmunoassay III. Results and Interpretation References 44 Relaxin I. Introduction II. Method of Radioimmunoassay III. Radioimmunoassay Characterization IV. Levels of Circulating Relaxin References Vasoactive Peptide Hormones 45 Renin and the Angiotensins I. Introduction II. Methods of Radioimmunoassay III. Verification of Assay Results and Special Problems IV. Commercial Kits and Concluding Comments References 46 Bradykinin I. Introduction II. Radioimmunoassay Methodology III. Validation and Standards References 47 Urogastrone-Epidermal Growth Factor I. Introduction II. Methods of Radioimmunoassay III. Urogastrone Measurements References 48 Nerve Growth Factor: Radioimmunoassay and Bacteriophage Immunoassay I. Background Information II. Radioimmunoassay III. Bacteriophage Immunoassay IV. Measurement of NGF in Cells and Biologic Fluids V. Summary References 49 Somatomedin A, Somatomedin C, and NSILA-s I. Introduction II. Preparation of Buffers and Columns for the Somatomedins A and C Assays III. Preparation of Placental Membranes IV. Technique of Radioreceptor Assay for Somatomedins A and C V. Preparation of Buffer and Column for the NSILA-s Assay VI. Technique of Radioreceptor Assay for NSILA-s VII. Cross-Reactivity with Other Growth Factors VIII. Measurement of Somatomedins A and C and NSILA-s in Blood References Appendixes I. Summary of Radioimmunoassay Methodology II. Commercial Sources of Radioimmunoassay Components III. Normal Values As Determined by Radioimmunoassay Index

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詳細情報

• NII書誌ID(NCID): BA14324809
• ISBN:
  • 0123792606
• LCCN: 78003340
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xxx, 1040 p.
• 大きさ: 24 cm
• 分類:
  • LCC : QP571
  • DC : 612/.405/0154582
• 件名:
  • LCSH : Hormones -- Analysis
  • LCSH : Radioimmunoassay
  • MESH : Hormones -- Analysis
  • MESH : Radioimmunoassay