Cerebral blood flow and metabolism

著者

書誌事項

Cerebral blood flow and metabolism

Lars Edvinsson, Eric T. MacKenzie, James McCulloch

Raven Press, c1993

大学図書館所蔵 件 / 全19件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Co-authored by three of the world's foremost authorities - all directors of the International Cerebral Blood Flow and Metabolism Society - this work is a text and reference on cerebral blood flow and metabolism. Unlike other books, which focus on a single aspect of cell metabolism or the cerebral circulation, this volume covers the entire field in a systematic and coherent way and synthesizes the diverse body of basic science and clinical literaturue. The reader should gain a complete understanding of the anatomical, physiological, and pharmacological bases of a cerebral circulation, its regulation in health and disease, and the pathophysiological disturbances occurring in cerebrovascular disorders. The value of the book is further enhanced by the authors' discussions of future directions for research and therapeutic intervention.

目次

  • Part 1 The anatomic bases: general and comparative anatomy of the cerebral circulation
  • the blood vessel wall - endothelial and smooth muscle cells
  • perivascular nerve fibres in brain vessels
  • functional circuitry. Part 2 The physiological bases: vascular smooth muscle reactivity in vitro and in situ
  • the blood-brain barrier - permeability and substrate transport
  • energy generation in the central nervous system
  • neurotransmitters - metabolic and vascular effects in vivo. Part 3 The pharmacological bases: adrenergic mechanisms
  • dopamine
  • 5-hydroxytryptamine
  • acetylcholine
  • histamine
  • adenosine
  • prostaglandins and other elcosanoids
  • calcium antagonists
  • anaesthetic agents
  • neuropeptides
  • aminobutyric acid (GABA)
  • glutamic acid. Part 4 Fundamental responses of the cerebral circulation: aspects on methods used in vivo
  • changes in arterial gas tensions
  • autoregulation - arterial and intracranial pressure
  • functional depression and stimulation. Part 5 Disordered control - pathophysiological aspects: disturbed cerebral autoregulation
  • disordered substrate supply
  • cerebral ischemia
  • migraine and cluster headache
  • subarachnoid haemorrhage
  • the aged brain.

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