書誌事項

Chiral separations by liquid chromatography

Satinder Ahuja, editor

(ACS symposium series, 471)

American Chemical Society, 1991

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注記

"Developed from a symposium sponsored by the Division of Analytical Chemistry at the 200th National Meeting of the American Chemical Society, Washington, D.C., August 26-31, 1990."

Includes bibliographical references and indexes

内容説明・目次

内容説明

A definitive reference for researchers working on problems involving chirality. Presenting state-of-the-art information, this volume covers all the major modes of separation and offers contributions from the leading researchers who developed these techniques. Four chapters provide a detailed review of the commonly used columns: brush type, cyclodextrin, polysaccaride carbonate, and protein. Many of the papers focus on HPLC, a technique which is also ideally suited for large scale preparation of optical isomers. In addition, the volume provides significant discussion on the use of chiral discriminators or selectors.

目次

  • Chiral Separations: Overview
  • Analytical Criteria for Chiral High-Pressure Liquid Chromatography
  • Commercially Available Brush-Type Chiral Selectors for the Direct Resolution of Enantiomers
  • Chiral Separations Using Native and Functionalized Cyclodextrin-Bonded Stationary Phases in High-Pressure Liquid Chromatography
  • Chromatographical Optical Resolution on Polysaccharide Carbamate Phases
  • Protein Column-Based Chiral Reversed-Phase Liquid Chromatography
  • Optimization of Chiral Separations on Silica-Bonded *a[1-Acid Glycoprotein by Mobile Phase Additives
  • Chiral Recognition on Biopolymer-Based High-Pressure Liquid Chromatographic Chiral Stationary Phases: A Case for Multiple Interaction Sites
  • Chiral Separations and Modes of Association of Hydrogen-Bonding Molecules
  • Liquid Chromatographical Separation of Enantiomers by Hydrogen-Bond Association
  • High-Pressure Liquid Chromatographic Resolution of Optical Isomers: Influence of Mobil and pi-Donor Chiral Stationary Phases
  • Direct Stereochemical High-Pressure Liquid Chromatographic Separation of Aminoglutethimide and Its Major Metbolite: Its Applications to Biological Fluids
  • Amino Acid Racemization: A Tool for Dating?

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