書誌事項

Molecular biology and its application to medical mycology

edited by Bruno Maresca, George S. Kobayashi, Hideyo Yamaguchi

(NATO ASI series, Series H . Cell biology ; vol. 69)

Springer-Verlag, c1993

  • : Berlin
  • : New York

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注記

"Proceedings of the NATO Advanced Research Workshop on Molecular Biology and Its Application to Medical Mycology, held at Taormina, Italy, January 6-8, 1992"--T.p. verso

"Published in cooperation with NATO Scientific Affairs Division."

Includes bibliographical references and index

内容説明・目次

内容説明

Presented here are recent achievements in the molecular biology of non-pathogenic yeast and filamentous fungi as well as human pathogens. The book is divided into four sections: molecular biology of yeast; molecular biology of filamentous fungi; new tools and prospectives for medical mycology; and fungal morphogenesis. It focuses on aspects of medical mycology; namely the isolation of specific genes and strategies for developing new targets for antifungal therapy.

目次

Molecular Biology of Yeast.- Cell Cycle Regulation in Fission Yeast.- Yeast Genes Overcoming Growth Arrest Induced by 1,10-Phenanthroline.- Reverse Genetics in a Non-Conventional Yeast, Candida maltosa.- The Complement C3D-Binding Receptor (CR2) of Candida albicans: Cloning and Sequence Analysis of a Gene Fragment Homologous with a Human CR2 cDNA Clone.- Biology, Physiology, Biochemistry and Molecular Genetics of Trichosporon Yeasts.- Physiological Functions of Vacuoles in Yeast: Mechanism of Sequestration of Metabolites and Proteins into Vacuoles.- Characterization of a Candida albicans-Specific DNA Fragment.- Recent Advances in the Molecular Biology of Cryptococcus neoformans.- Molecular Biology of Kluyveromyces lactis.- Gene Regulatory Circuits in S. cerevisiae as a Tool for the Identification of Heterologous Eukaryotic Regulatory Elements.- Molecular Biology of Filamentous Fungi.- Molecular Breeding in Filamentous Fungi with Emphasis on Aspergilli.- TubB ?-Tubulin is Essential for Sexual Development in Aspergillus nidulans.- The Heat Shock Response of Neurospora crassa.- Blue Light Regulated Expression of Geranylgeranyl Pyrophosphate Synthetase (Albino-3) Gene in Neurospora crassa.- Expression of Genes for the Biosynthesis of Penicillin.- New Tools and Prospectives for Medical Mycology.- Imaging of the Yeast Killer Phenomenon.- cDNA Cloning of Candida albicans Aspartic Proteinase and Its Diagnostic Application.- Molecular Biotyping of Candida in Experimental and Clinical Studies.- Homoserine Dehydrogenase as a Selective Target Molecule for Antifungal Action.- Molecular Mechanisms of Antifungal Activity and Fungal Resistence: Focus on Inhibitors of Ergosterol Biosynthesis.- Molecular Studies on Azole Sensitivity in Fungi.- Antifungal Chemotherapy and Drug Strategies: Projected Clinical Needs.- Funding Medical Mycology: Strategies for Attracting the Private Sector.- Fungal Morphogenesis.- Chromosomal Organization of Histoplasma capsulation.- Chitin, Chitin Synthase and Chitin Synthase Conserved Region Homologues in Wangiella dermatitidis.- Heat Shock Response and Adaptation during Morphogenesis in Histoplasma capsulatum.

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