Methods to assess DNA damage and repair : interspecies comparisons
Author(s)
Bibliographic Information
Methods to assess DNA damage and repair : interspecies comparisons
（SCOPE, 52）（SGOMSEC, 8）
J. Wiley, c1994
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Note
"IPCS joint activity ; 19"
Includes bibliographical references and index
Description and Table of Contents
Description
This volume is concerned with a subject basic to chemical risk assessment: DNA damage and repair, taking account of interspecies differences. It evaluates current knowledge of the mechanisms of the activation and detoxication of DNA damaging agents, organotropic and cell-structure effects, induction and repair of DNA damage, and the molecular and phenotypical analysis of mutation induction. The report includes general recommendations aimed at improving research in this field and developing methodologies for genotoxicity testing, taking account of the potentials and limitations of available animal models.
Table of Contents
- JOINT REPORT: Introduction, General Conclusions and Recommendations
- DNA Damage
- CONTRIBUTED CHAPTERS: DNA Adducts and their Consequences
- Nucleotide Excision-Repair Among Species
- DNA Repair in Specific Sequences and Genomic Regions
- Molecular Analysis of Mutations in Shuttle Vectors and Transgenic Animals.
by "Nielsen BookData"