Tuberculosis : pathogenesis, protection, and control

著者

書誌事項

Tuberculosis : pathogenesis, protection, and control

editor, Barry R. Bloom

ASM Press, c1994

大学図書館所蔵 件 / 全9件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The reemergence of tuberculosis is now a major health problem around the world. This often fatal disease persists as the largest cause of death from a single infectious agent. The editor, a leading figure in tuberculosis research, has gathered a team of acknowledged scientific and clinical experts from around the world to bring together the most current body of information on all aspects of tuberculosis its global importance, epidemiology, molecular biology, and immunology. The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease. Tuberculosis is necessary reading for all microbiologists, clinicians, and public health officials concerned with the resurgence and spread of tuberculosis. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

目次

  • Introduction to Tuberculosis
  • The global problem
  • History of tuberculosis
  • Overview of clinical tuberculosis, Epidemiology of tuberculosis
  • Current laboratory diagnosis of tuberculosis
  • Animal models of tuberculosis
  • Biohazard considerations
  • Mycobacteriophages
  • Plasmids
  • Transposons, insertion elements and restriction polymorphisms
  • Approach to genomic structure
  • Expression of foreign genes in mycobacteria
  • Genetic strategies for analyzing virulence
  • The Physiology of M tuberculosis
  • Ultrastructure
  • Lipids and carbohydrates of M tuberculosis
  • Proteins and antigens of M tuberculosis
  • Metabolism of M tuberculosis
  • Transport in M tuberculosis
  • The Immunology of Tuberculosis
  • Immune mechanisms of protection
  • T cell responses and lymphokines
  • B and T cell recognition
  • Pathogenesis of tuberculosis
  • Pathogenesis of tuberculosis in AIDS
  • New Approaches to Prevention and Treatment of Tuberculosis
  • Molecular approaches to diagnosis
  • BCG and new approaches to vaccines for tuberculosis
  • Search for new drugs
  • Molecular epidemiology
  • Operational and economic issues
  • Cultivation of M tuberculosis

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