Lipid mediators in the immunology of shock

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Lipid mediators in the immunology of shock

edited by M. Paubert-Braquet ... [et al.]

(NATO ASI series, Series A . Life sciences ; v. 139)

Plenum Press, c1987

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注記

"Proceedings of a NATO Advanced Research Workshop on Lipid Mediators in Immunology of Burn and Sepsis, held July 20-25, 1986, in Helsingor, Denmark"--T.p. verso

"Published in cooperation with NATO Scientific Affairs Division."

Includes bibliographies and index

内容説明・目次

目次

I - Burn, Sepsis and Shock Overviews.- Burn and Sepsis: Immunological Overview.- Burns: Clinical and Biological Overview.- Infection: Cause or Effect of Pathophysiologic Change in Burn and Trauma Patients.- Biochemical Mediators in Acute Respiratory Distress Syndrome (ARDS) After Burning Injury.- "Sepsis Parameters" in Patients with Lethal Burn.- Computer Assisted 10 MHZ Sonography of Burn Depth in Man - A Quantitative Guide For the Surgical Strategy of Sepsis Prevention.- Pharmacological Control of Hemorrhagic Shock : Does Hypertonic Resuscitation Qualify ?.- 2 - Mediators of Burn and Sepsis.- Oxygen, Free Radicals, Shock and Trauma.- Role of Free Radical Lipid Peroxidation in Burn and Endotoxin Shock.- The Significance of Pentane Measurements in Man.- Detection of Pentane as a Measurement of Lipid Peroxidation in Humans Using Gas Chromatography With a Photoionization Detector.- Eicosanoids and The Pathophysiology of Sepsis and Trauma.- Lipid Metabolism During Starvation and Sepsis in Relation to Fatty Acid Profile in Liver and ?-Linolenic- and ?-Linolenic Acid-Enriched Diets.- Pathophysiology of Renal Failure in Shock: Role of Lipid Mediators.- Multiple Organ Failure, Liver Failure and Polyunsaturated Fat Metabolism.- Leukotrienes in Endotoxin Shock.- Time-Dependent Appearance of LTB4 in Human Burn Blisters.- Platelet-Activating Factor : An Inflammatory Mediator Involved in the Pathophysiology of Shock.- Mechanisms of Circulatory Collapse Induced by Paf-Acether.- Lipid Mediators in Lung Anaphylaxis : Kinetics of Their Release and Modulation by Selected Drugs.- A Role for Platelet Activating Factor in Shock and Acute Lung Injury.- Morphological and Pharmacological Evidences for the Participation of Paf-Acether in Anaphylactic Shock in the Guinea-Pig.- Biogenic Amines : Microcirculatory Aspects in Shock, Sepsis and Trauma.- Trypsin-Like Activity in Burn and Sepsis.- Significance of the Activation of the Kinin System Following Thermal Injury.- The Role of Lipid Mediators in Blood Fibrinolysis.- Fibrinolysis in Endotoxemia.- 3-The Immune Response in Critically Ill Patients.- Origins of Immunological Impairments in Burns.- Importance of Immune Function in Trauma for Survival.- Anergy in Critically Ill Patients.- Neural Release Mechanisms of the Injury Response.- Surgery and the Immune Response.- Immune Function and Severe Infection.- 4 - Mechanisms of Immune Response Impairment in Critically Ill Patients.- Interleukins: An Overview.- Cellular Immune Function and Injury.- Metabolic Mediators in Injury.- Mediators Affecting IL2 Function in Burn Immunosuppression.- T Cell Subpopulations Following Thermal Injury : Effect of the Acute Stress Response.- Natural Killer Cell Activity and Lymphocyte Function During and After Open-Heart Surgery in Relation to the Endocrine Stress Response.- Natural Killer Cell Activity During Epinephrine and Cortisol Infusion in Healthy Volunteers.- A Longitudinal Study of the Influence of Acute Myocardial Infarction on Natural Killer Cells.- Immune Depression and Sepsis Following Injury : The Role and Identity of Circulating Mediators.- Elective Immunosuppression.- Characterization of the Induction of Human Interleukin 1 by Endotoxins.- Human Endothelial Cells Produce Platelet Activating Factor in Response to Interleukin 1.- Interleukin 1 Stimulation of Vascular Endothelial Cell Adhesiveness for Leucocytes: in vitro and in vivo studies.- Systemic Alteration of Endothelial Cells in Shock.- Arterial Wall Reaction Following Electrical Local De-Endothelialization.- 5 - The Role of Lipid Mediators in the Immune Response.- The Role of Platelet Activating Factor in the Immune Response.- Leukotrienes in Lymphocyte Activation : Leukotriene B4, Enhances Interleukin 2 and Interferon-Gamma Production by Mitogen and A1loantigen-Stimulated Human T Cells.- Regulation of T Cell Activation by Leukotriene B4.- A Role for Platelet-Activating Factor (PAF) in Human T-Lymphocyte Proliferation.- 6 - New Drugs in Shock.- Lack of Effect of Cyclosporin A on Endogenous Arachidonic Acid Metabolism in Human Neutrophils.- Sulotroban (BM 13.177) and BM 13.505, Two TX-Receptor Blockers, Are Effective in Experimental Models of Ischaemia and Shock.- Ginkgo Biloba extracts Inhibits Oxygen Species Production Generated by Phorbol Myristate Acetate Stimulated Human Leukocytes.- The Coronary, Inotropic, Chronotropic and Arrhythmogenic Effects of PAF-Acether on Isolated Guinea-Pig Heart and Their Selective Inhibition by BN 52021.- The Effect of BW 755C on Would Healing in a Scald Burn Injury Pig Model-Morphological and Biochemical Findings.- A New Sonographic Model for Effective Quantification of Anti-Edematous and Antiinflammatory Drugs in Burns.

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