Oral cephalosporins
著者
書誌事項
Oral cephalosporins
（Antibiotics and chemotherapy, vol. 47）
Karger, 1995
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci or Bacteroides species. Many, however, are suitable for treating infections of the respiratory and urinary tracts and of the skin and its structure, as well as certain sexually-transmitted diseases. Authors consider other possible uses, against multi-resistant Enterobacteriaceae for instance, but also point out the limitations of the oral cephalosporins. For those working in the fields of infectious disease, bacteriology, chemotherapy, pharmaceutics and pharmacokinetics, this book is a valuable source of authoritative information.
目次
- Systematics of beta-lactams - chemical properties and structure activity relationship of oral cephalosporins, F. Kees and H. Grobecker
- pharmacology and toxicology of oral cephalosporins, G. Gialdroni Grassi
- clinical pharmacokinetics of oral cephalosporins, K. Stoeckel et al
- microbiology of oral cephalosporins, W. Cullmann
- oral cephalosporins in upper respiratory infections, E. Leibovitz and R. Dagan
- oral cephalosporins - clinical results in lower respiratory tract infections, E. Pozzi and A. Oliva
- oral cephalosporins - clinical results in urinary tract infections, H. Giamarellou
- tolerability of oral cephalosporins, H. Lepper and C.-J. Estler.
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