The metabolism and toxicity of fluoride
著者
書誌事項
The metabolism and toxicity of fluoride
（Monographs in oral science, vol. 16）
Karger, 1996
2nd, rev. ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Since the first edition of this highly-acclaimed book appeared in 1989, a considerable amount of new information has been published on the diverse effects that fluoride can produce in biological systems. The remarkable decline in dental caries that is now occurring throughout the world can be largely attributed to the use of ingested and topical forms of fluoride. Indeed, fluoride is now widely regarded as the cornerstone of modern preventive dentistry. In addition to its prophylactic qualities, fluoride is currently being investigated for its benefits in the treatment of osteoporosis, ischemia, and other major diseases; in larger doses, however, fluoride is known to cause fluorosis, and in excessive amounts can even lead to death. This newly revised edition includes data from the most recent studies in these areas and provides an up-to-date, critical discussion of fluoride metabolism and toxicity as well as environmental and physiological variables that can affect these processes. It will be of particular interest to dental students and residents, dental educators and researchers, toxicologists, pharmacologists and physiologists.
目次
- Overview of fluoride metabolism and intake
- absorption and plasma concentrations of fluoride
- soft tissue distribution of fluoride
- renal handling of fluoride
- factors that modify the metabolism or effects of fluoride
- dental caries and fluoride in the oral environment
- acute fluoride toxicity
- chronic fluoride toxicity.
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