Multidrug resistance in cancer cells : molecular, biochemical, physiological, and biological aspects
著者
書誌事項
Multidrug resistance in cancer cells : molecular, biochemical, physiological, and biological aspects
Wiley, c1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The emergence of resistant cancer cells after repeated courses of chemotherapy is exacerbated by the development of multidrug resistance and has reduced the promise of combination chemotherapy. This book considers the clinical and scientific implications of resistance on cancer treatment.
目次
CHARACTERIZATION, EXPRESSION AND FUNCTIONS OF TRANSPORTERS IN MDR. Functional and Molecular Characterization of the Human Multidrug Transporter (C. Hrycyna, et al.). Regulation of MDR Genes (M. Cornwell). Chromosomal and Extrachromosomal Localization of Human MDR Genes (P. Schoenlein) The Role of Topoisomerase II in Multidrug Resistance (S. Yamada K. Ando). Non-PKC Kinases and Multidrug Resistance (I. Abraham). REVERSAL OF MULTIDRUG RESISTANCE. Multidrug Resistance-reversing Agents for Potential Clinical Use (O. Nakanishi T. Tsuruo). Reversal of MDR in Solid Tumors (G. Gianccone H. Pinedo). Index.
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