書誌事項

The integrated immune system

editor-in-chief, Leonore A. Herzenberg ; senior and founding editor, Donald M. Weir ; co-editors, Leonard A. Herzenberg, Caroline Blackwell

(Weir's handbook of experimental immunology, v. 4)

Blackwell Science, c1996

5th ed

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内容説明・目次

内容説明

The new fifth edition of the highly acclaimed Handbook of Experimental Immunology has been completely restructured and extensively revised to reflect the considerable increase in the importance of immunology as a research discipline. Produced in four volumes, which are available for separate purchase, or as a set, the text provides a complete reference which includes experimental protocols and explications of general principles. Each section contains overviews, and chapters describing the background and technical detail of a comprehensive range of immunological procedures in immunochemistry, cellular immunology, genetics and molecular immunology, and the application of immunological methods. It is also available on CD-ROM. All material available within the four-volume

目次

  • Volume IV: The Integrated Immune System
  • List of Contributors
  • Foreword
  • Preface
  • Section 24: Transgenic, Knockout, and Gene Targeted Mice: 144. Overview: Transgenic, Knockout, and Gene Targeted Mice
  • 145. Recently Developed Techniques for Manipulating the Mouse Germline and Analyzing Mutant Phenotypes
  • 146. Immunologically Humanized Transgenic Mice
  • 147. In Vitro Differentiation of Embryonal Stem Cells as a Tool for the Study of Hematopoiesis
  • 148. Gene Therapy in the Lymphohematopoietic System
  • Section 25. Specialized Mouse Strains and Study of Gene Expression and Function: 149. Overview: Specialized Mouse Strains and Study of Gene Expression and Function: 150. Single Gene Mouse Models of Immunodeficiency and Autoimmune Diseases
  • 151. H-2 Mutations
  • 152. Minor Histocompatibility Loci - Congenic Strains
  • Section 26. The Myeloid System: 153. Overview: The Myeloid System
  • 154. Murine Macrophages: Isolation, Cultivation, Characterization
  • 155. Human Monocytes: Isolation, Cultivation, Applications
  • 156. Dendritic Cells
  • 157. Neutrophil Granulocytes
  • 158. Isolation, Cultivation, Characterization: Eosinophils
  • 159. Isolation, Cultivation, Characterization: Mast Cells
  • 160. Growth and Differentiation of Murine Macrophages
  • 161. Migration and Adhesion in Vivo: Myeloid Cells
  • 162. Dendritic Cells: Migration In Vivo
  • 163. Locomotion and Chemotaxis in Vitro
  • 164. Assays of Transendothelial Migration of Leukocytes
  • 165. Selective Depletion of Macrophages by Liposome-Encapsulated Drugs
  • 166. Methods for Studying the Cellular Binding Properties of Lectin-Like Receptors
  • 167. Phagocytosis and Intracellular Kiling of Microorganisms by Polymorphonuclear and Mononuclear Phagocytes
  • 168. Endocytosis and Vacuolar Function
  • 169. Current Methodology in the Study of Signal Transduction
  • 170. Gene Expression and Secretory Function
  • 171. Reactive Oxygen and Nitrogen Metabolites and Related Enzymes
  • 172. Mouse Macrophage Cell Lines
  • 173. Human Myeloid Cell Lines
  • 174. Markers of Rodent Myeloid Cells
  • 175. Cluster Designation Antigens Expressed on Myeloid Lineage Cells
  • Section 27 Acquired and Genetic Immunodeficiencies: 176. Overview: Acquired and Genetic Immunodeficienceis: Informative Experiments of Nature
  • 177. The Acquired immunodeficiency Syndrome (AIDS)
  • 178. Severe Combined Immunodeficiencies
  • 179. X-Linked Immunodeficiencies
  • 180. Phagocytic Defects
  • 181. The Genetically Determined and Acquired Defects in the Complement System
  • 182. Flow Cytometric Evaluation in AIDS
  • 183. Common Variable Immunodeficiency and IgA Deficiency
  • Section 28 Neurobiology and Immunology: 184. Overview: Neurobiology and Immunology
  • 185. The Oligodendrocyte-Type-2 Astrocyte (O-2A) Progenitor Cell: From Rodent Glial Precursor to Human Glial Neoplasia
  • 186. Perinatal to Adult Transition in Precursor Populations of the Oligodendrocyte-Type-2 Astrocyte (0-2A) Lineage
  • 187. Analysis of Trk/Neurotrophin Receptor Activity
  • 188. Repairing CNS Demyelination by Glial Cell Transplantation
  • 189. Isolation of Precursor Cells and Neuroblasts from Embryonic and Adult Central Nervous System
  • 190. Neuronal Development in an Immortalized Sympathoadrenal Cell Line
  • Section 29: Immunotherapy with Monospecific Antibodies: 191. Overview: Immunotherapy with Monospecific Antibodies
  • 192. Immunotherapy of Murine Collagen-Induced Arthritis
  • 193. Selective Immunotherapy of Autoimmune Disease with Antibodies-to-Cell Adhesion Receptors: Lessons from Experimental Autoimmune Encephalomyelitis and Insulin-Dependent Diabetes Mellitus
  • 194. Mice Engineered with Human Immunoglobulin YACs: A New Technology for Production of Fully Human Antibodies for Autoimmunity Therapy
  • 195. Immunotherapy with Monoclonal Anti-CD4 Antibodies
  • Section 30 Tumor Immunology: 196. Overview: Tumor Immunology
  • 197. Tumor Cell Lines for Studies in Tumor Immunology
  • 198. Natural Killer Cells and Their Role in Tumor Immunology
  • 199. Cytokines and the Treatment of Cancer
  • 200. Cytokine Gene-Transduced Tumor Cell Vaccines
  • 201. Immune Conjugates in Immunotherapy
  • 202. Radionuclide-Immune Conjugates for Immunoscintigraphy and Immunotherapy
  • Section 31 Immunohistochemistry and Immunopathology: 203. Overview: Immunohistochemistry and Immunopathology
  • 204. A Step by Step Guide to In Situ Immune Response Analysis of Lymphoid Tissues by Immunohistochemical Methods
  • 205. Immunofluorescence and Confocal Laser Scanning Microscopy
  • 206. Micromanipulation and PCR Analysis of Single Cells from Tissue Sections
  • 207. In Situ Hybridization
  • 208. Immunogold Labeling of Ultrathin Cryosections: Application in Immunology
  • 209. Methodology of Lymphocyte Kinetics
  • 210. Immunopathology
  • Section 32 Immunopharmacology: 211. Overview: Immunopharmacology
  • 212. Assays for Small Molecules with Immunosuppressive Activity
  • 213. Mediator Release by Mast Cells and Basophils
  • 214. Assays for Cyclooxygenase Inhibition by Nonsteroidal Anti-Inflammatory Drugs
  • 215. Leukotriene Synthesis Inhibition
  • 216. Platelet-Activating Factor: Biological Significance, Laboratory Assays, and Antagonists
  • 217. Assays for Kinins and Kinin Antagonists
  • 218. Complement Activation and Inhibition
  • 219. Inhibition by Small Molecules of the Production of the Pro-Inflammatory Cytokines TNF-a and IL-1B
  • Section 33 Cytokine Functions in the Immune System: 220. Overview: Cytokine Functions in the Immune System
  • 221. Interleukin-1
  • 222. Transforming Growth Factor-Beta: An Anti-Inflammatory Cytokine In Vitro and In Vivo
  • 223. IL-13 is Structually and Functionally Related to IL-4: Redundancy of Anti-Inflammatory Properties on Monocytes, but Lack of T Cell Stimulatory Activities
  • 224. Polyclonal Activation of Human Mature B Lymphocytes
  • 225. Regulation of IgE Synthesis by Cytokines
  • 226. Role of Cytokines in Determing T Cell Function (Mouse)
  • 227. Role of Cytokines in Determing Human T Cell Function
  • 228. Role of Cytokines in Murine Thymic Maturation

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詳細情報

  • NII書誌ID(NCID)
    BA29549212
  • ISBN
    • 0865425728
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    Cambridge, Mass.
  • ページ数/冊数
    1 v. (various pagings)
  • 大きさ
    29 cm
  • 親書誌ID
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