Gene therapy for diseases of the lung

書誌事項

Gene therapy for diseases of the lung

edited by Kenneth L. Brigham

(Lung biology in health and disease, 104)

M. Dekker, c1997

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.

目次

Overview Human Gene Therapy: The Initial Concepts, W. French Anderson Discovering Genes That Cause Disease, Francis S. Collins Delivering Genes to Human Lungs Adenoviral Vectors for Gene Therapy of Inherited and Acquired Disorders of the Lung, David T. Curiel and Robert I. Garver, Jr. Adeno-Associated Virus-Based Delivery Systems, Pamela L. Zeitlin Cellular Responses to Adenovirus Entry, Susanna Chiocca and Matthew Cotton Catonic Lipid-Based Gene Delivery: An Update, Xiang Gao Liposome/Viral Hybrid Gene Delivery Systems, Arlene A. Stecenko Gene Therapy in the Lung: The Next Generation Manipulating the Intracellular Trafficking of Nucleic Acids, Kathleen E. B. Meyer, Lisa S. Uyechi, and Francis C. Szoka, Jr. Delivery of Genes Through the Lung Circulation, David M. Rodman and Elizabeth G. Nabel Targeting Gene Expression to the Lung, Jeffrey A. Whitsett and Stephan W. Glasser Strategies to Accomplish Targeted Gene Delivery Employing Tropism-Modified Adenoviral Vectors, Joanne T. Douglas and David T. Curiel Disease-Directed Gene Therapy Toward Correction of the Genetic Defect in Cystic Fibrosis, Larry G. Johnson and Richard C. Boucher Correction of the Genetic Defect in Alpha-1 Antitrypsin Deficiency by Somatic Gene Therapy, Randy C. Eisensmith and Savio L. C. Woo Gene Therapy for Chronic Inflammatory Diseases of the Lungs, Angelo E. Canonico Gene Therapy for Acute Diseases of the Lungs, Kenneth L. Brigham Gene Therapy for Lung Cancer, Choon-Taek Lee and David P. Carbone Epilogue The Regulatory Process and Gene Therapy, Suzanne Epstein Some Issues Affecting Progress Toward Human Gene Therapy and Potential Application to the Lung, Theodore Friedmann

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