Controlled drug delivery : challenges and strategies

Author(s)

• Park, Kinam

Bibliographic Information

Controlled drug delivery : challenges and strategies

Kinam Park, editor

（ACS professional reference book）

American Chemical Society, c1997

Note

Includes bibliographical references and index

Description and Table of Contents

Description

This volume discusses the challenges of creating controlled release dosage forms that will deliver new therapeutic agents based on high-molecular-weight molecules. It examines strategies for delivering drugs through resistant biological barriers and surveys a variety of topics, including drug targeting, self-regulated drug delivery, protein drug delivery, biosensors, cell and tissue engineering, new biomaterials, modeling methods, pharmacokinetics, and U.S. federal regulations.

Table of Contents

• CONTROLLED DRUG DELIVERY: PAST, PRESENT, AND FUTURE
• INTRACELLULAR DELIVERY AND TARGETING
• 2. Intracellular Delivery of Peptides and Proteins
• 3. DNA Delivery Vectors for Somatic Cell Gene Therapy
• 4. Targetable Polymeric Drugs
• 5. Particle Engineering of Biodegradable Colloids for Site-Specific Drug Delivery
• 6. Site-Specific Drug Delivery in the Gastrointestinal Tract
• SELF-REGULATED DRUG DELIVERY
• 7. Feedback-Controlled Drug Delivery
• 8. Stimuli-Sensitive Drug Delivery
• 9. Sensocompatibility: Design Considerations for Biosensor-Based Drug Delivery Systems
• DELIVERY OF PEPTIDE AND PROTEIN DRUGS
• 10. Formulation of Proteins and Peptides
• 11. Stability of Peptides and Proteins
• 12. Peptide, Protein, and Vaccine Delivery from Implantable Polymeric Systems
• 13. Oral Immunization Using Microparticles
• 14. Peptide and Protein Delivery for Animal Health Applications
• TISSUE ENGINEERING AND GENE THERAPY
• 15. Protein Delivery by Microencapsulated Cells
• 16. Tissue Engineering: Integrating Cells and Materials To Create Functional Tissue Replacements
• 17. Drug Delivery Using Genetically Engineered Cell Implants
• 18. Ribozymes as Antiviral Agents
• NEW BIOMATERIALS FOR DRUG DELIVERY
• 19. Pseudo-Poly(amino acid)s: Examples for Synthetic Materials Derived from Natural Metabolites
• 20. Transductional Protein-Based Polymers as New Controlled-Release Vehicles
• 21. Synthetically Designed Protein Polymer Biomaterials
• 22. Biological Effects of Polymeric Drugs
• 23. New Biodegradable Polymers for Medical Applications: Elastomeric Poly(phosphoester-urethane)s
• 24. "Intelligent" Polymers
• MODELING OF CONTROLLED DRUG DELIVERY
• 25. Modeling of Self-Regulating Oscillatory Drug Delivery
• 26. Modeling Studies of Future Controlled-Release Devices
• 27. Computer Dynamics Simulation of Controlled Release
• REGULATORY ISSUES
• 28. Food and Drug Regulations for Controlled-Release Dosage Forms
• 29. Pharmacodynamic and Pharmacokinetic/ Considerations in Controlled Drug Delivery

by "Nielsen BookData"

Details

• NCID: BA31948957
• ISBN:
  • 0841234183
• LCCN: 96051016
• Country Code: us
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Washington, DC
• Pages/Volumes: xvii, 629 p.
• Size: 24 cm
• Classification:
  • LCC : RS199.5
  • DC21 : 615/.6
• Subject Headings:
  • LCSH : Drug delivery systems
  • LCSH : Drugs -- Dosage forms
• Parent Bibliography ID:
  • BA04443415