The pharmacology of pain
著者
書誌事項
The pharmacology of pain
（Handbook of experimental pharmacology, v. 130）
Springer, c1997
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
There have been many advances in the pharmacology of pain, both in terms of mechanisms of transmission and events un-derlying the production of analgesia. This volume provides an overview of the field covering the basic science of pain and its applications. The chapters range from the peripheral events through to central mechanisms, with emphasis on the transmitters and receptors implicated in transmission and control. The book covers acute, inflammatory and neuropathic pain states and each chapter links the basic aspects with the therapeutic applications, both in terms of drug development and clinical approaches.
目次
- Animal models of analgesia
- peripheral mediators of pain
- non-steroidal anti-inflammatory drugs and pain
- the sympathetic nervous system and pain
- excitability blockers - anticonvulsants and low concentration local anaesthetics in the treatment of chronic pain
- tachykinins - central and peripheral effects
- growth factors and pain
- mechanisms of central hypersensitivity
- novel modulators in nociception
- pharmacological studies of nociceptive systems using the C-Fos immunohistochemical technique
- molecular aspects of opioid receptors
- opioid pharmacology of acute and chronic pain
- opioid problems, and morphine metabolism and excretion
- inhibitory neurotransmitters and nociception
- role of descending noradrenergic and serotoninergic pathways in the modulation of nociception
- neonatal pharmacology of pain.
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