Drug-drug interactions : Scientific and regulatory perspectives

著者

• Li, Albert P.

書誌事項

Drug-drug interactions : Scientific and regulatory perspectives

edited by Albert P. Li

（Advances in pharmacology / edited by Silvio Garattini [and] Parkhurst A. Shore, vol. 43）

Academic Press, c1997

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Drug Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug drug interactions, the prediction of drug drug interaction potential of new drugs, and the avoidance of clinically significant drug drug interaction in patients.

目次

J. Collins, Foreword.A.P. Li, Preface.A.P. Li, Overview: Scientific Basis of Pharmacokinetic Drug-Drug Interactions.F.P. Guengerich, Role of Cytochrome P450 Enzymes in Drug-Drug Interactions.J.M. Sauer, E.R. Stine, L. Gunawardhana, D.A. Hill, and I.G. Sipes, The Liver as a Target for Chemical-Chemical Interactions.A.D. Rodrigues and S.L. Wong, Applications of Human Liver Microsomes in Metabolism-Based Drug-Drug Interactions.A.P. Li, Applications of Human Hepatocytes as an Experimental System for the Evaluation of Pharmacokinetic Drug-Drug Interactions.J.L. Ferrero and K. Brendal, Liver Slices as a Model in Drug Metabolism and Drug-Drug Interactions.C.L. Crespi and B.W. Penman, The Use of cDNA Expressed Human Cytochrome P450 Enzymes to Study Potential Drug-Drug Interactions.G.L. Kedderis, Pharmacokinetics of Drug Interactions.T.N. Thompson, Experimental Models for Evaluating Enzyme Induction Potential of New Drug Candidates in Animals and Man and a Strategy for Their Use.J.D. Balian, Metabolic Drug-Drug Interactions: Perspective from U.S. FDA Medical and Clinical Pharmacology Reviewers.M. Jurima-Romet, Drug Interactions: Perspectives of the Canadian Directorate.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA32772732
• ISBN:
  • 0120329441
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: San Diego
• ページ数/冊数: xviii, 304 p.
• 大きさ: 24 cm
• 親書誌ID:
  • BA10974234