Principles of medical pharmacology
著者
書誌事項
Principles of medical pharmacology
Oxford University Press, 1998
6th ed
大学図書館所蔵 全28件
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  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
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  広島
  山口
  徳島
  香川
  愛媛
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  福岡
  佐賀
  長崎
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is the Sixth Edition of a teaching text that has undergone continuous evolution and improvement since 1975. It has been extensively revised, enlarged and updated to reflect the latest research. The authors have "pre-tested" it in their own courses to ensure accessibility and clarity of presentation. Though aimed primarily at medical students, the text has also found wide acceptance in pharmacology courses for students in biological sciences, pharmacy and dentistry, and among practicing pharmacists and physicians. The text covers all aspects of medical pharmacology, including a comprehensive discussion of the clinically important features of pharmacokinetics. It also provides a detailed treatment of topics that are often given less attention in similar texts, such as drug abuse and dependence, behavioral pharmacology, drug interactions, neonatal and geriatric pharmacology, and new drug development. This new edition features a number of improvements over its predecessors. Each chapter in the systems pharmacology section now begins with a brief case history that is meant to stimulate the reader's interest by demonstrating the clinical relevance of basic pharmacology.
New overview chapters and sections have been added on second messenger systems, and on the functional organization of the nervous, cardiovascular, gastrointestinal, and immune systems. The chapter on antiparasitic agents has been expanded to include organisms and drugs with relevance to many parts of the world. Extensive sections on current chemotherapy of HIV infection and AIDS along with discussions of new agents for drug-resistant tuberculosis, malaria and cancer; inflammatory bowel disease; and genetics of drug metabolism appear for the first time in the Sixth Edition. Due attention has been paid to new drugs being tested in North America and Europe that will probably be on the market soon.
目次
- I. GENERAL PRINCIPLES OF PHARMACOLOGY
- 1. Introduction to General Pharmacology
- 2. Drug Solubility, Absorption, and Movement Across Body Membranes
- 3. Drug Distribution
- 4. Drug Biotransformation
- 5. Pharmacokinetics
- 6. Clearance: The Quantitative Basis of Dosage
- 7. Drug Clearance by Specific Organs
- 8. Dose-Response Relationships
- 9. Drug Receptors
- 10. Signal Transduction and Second Messengers
- 11. Selectivity of Drug Action
- 12. Human Pharmacogenetics
- II. AUTONOMIC NERVOUS SYSTEM AND NEUROMUSCULAR JUNCTION
- 13. Autonomic Nervous System Neurotransmitters
- 14. Autonomic Cholinergic Agonists
- 15. Autonomic Cholinergic Antagonists
- 16. Adrenoceptor Agonists
- 17. Adrenoceptor Antagonists
- 18. Drugs Acting on Adrenergic Neurons (Adrenergic Neuronal Blocking Drugs)
- 19. Neuromuscular Transmission and Drugs (Muscle Relaxants)
- III. CENTRAL NERVOUS SYSTEM
- 20. Functional Organization of the Central Nervous System
- 21. Agents Modifying Movement Control
- 22. Antiseizure Drugs
- 23. Opioid Analgesics and Antagonists
- 24. General Anesthetics
- 25. Local Anesthetics
- 26. The Alcohols
- 27. Anxiolytics and Hypnotics
- 28. Antipsychotics
- 29. Antidepressant and Mood Stabilizing Agents
- 30. Hallucinogens and Psychotomimetics
- IV. MEDIATORS AND MODIFIERS OF TISSUE RESPONSES
- 31. The Eicosanoids
- 32. Autacoids
- 33. Histamine and Antihistamines
- 34. Anti-Inflammatory Analgesics
- V. CARDIOVASCULAR SYSTEM
- 35. Cardiovascular System Overview and Organization
- 36. Digitalis Glycosides and Other Positive Inotropic Agents
- 37. Antiarrhythmic Drugs
- 38. Vasodilators
- 39. Hyperlipoproteinemias and Antihyperlipidemic Drugs
- VI. RESPIRATORY, RENAL, AND BLOOD SYSTEMS
- 40. Drugs and the Respiratory System
- 41. Diuretics
- 42. Drugs Affecting Hemostasis
- 43. Drugs Affecting Erythropoiesis
- VII. GASTROINTESTINAL SYSTEM
- 44. Pharmacotherapy of Acid-Peptic Disorders
- 45. Drugs Used in the Treatment of Intestinal Motility Disorders and Inflammatory Disease
- 46. Drugs, Alcohol and the Liver
- VIII. ENDOCRINE SYSTEMS
- 47. Vasopressin, Oxytocin, and Uterotonic Drugs
- 48. Thyroid Hormones and Antihyperthyroid Drugs
- 49. Gonadotropic and Gonadal Hormones
- 50. Insulin and Oral Hypoglycemic Drugs
- 51. Adrenocortical Steroid Hormones
- IX. ANTI-INFECTIVE CHEMOTHERAPY
- 52. Principles of Antimicrobial Therapy
- 53. Antimicrobial Agents That Act upon Bacterial Cell Wall Formation
- 54. Antimicrobial and Antifungal Agents That Act upon Cell Membranes
- 55. Antimicrobial Agents That Affect the Synthesis of Cellular Proteins
- 56. Drugs Affecting Cellular Nucleic Acid Synthesis
- 57. Chemotherapy of Common Parasitic Infections
- 58. Antiviral Agents
- 59. Antiseptics, Disinfectants, and Sterilization
- X. ANTINEOPLASTIC CHEMOTHERAPY, IMMUNOPHARMACOLOGY
- 60. Antineoplastic Drugs
- 61. Immune System Organization, Modulation, and Pharmacology
- XI. SPECIAL TOPICS OF PHARMACOLOGY
- 62. Sources of Individual Variation in Drug Response
- 63. Adverse Drug Reactions
- 64. Drug Interactions
- 65. Perinatal Pharmacology
- 66. Geriatric Clinical Pharmacology
- 67. Vitamins
- 68. Drugs Altering Bone Metabolism
- 69. Chemical Carcinogenesis
- 70. Chemical Teratogenesis
- 71. Behavioral Pharmacology
- 72. Drug Abuse and Drug Dependence
- 73. Principles of Toxicology
- 74. Poisonings and Antidotal Therapy
- 75. Drug Development and Regulations
- INDEX
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