Viral infections of the nervous system

書誌事項

Viral infections of the nervous system

Richard T. Johnson

Lippincott-Raven, c1998

2nd ed

大学図書館所蔵 件 / 15

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

A classic neurovirology text by one of the world's foremost leaders in the field is now in its thoroughly revised, updated Second Edition. Dr. Johnson has rewritten every chapter of his groundbreaking book, synthesizing recent findings in molecular biology, neurobiology, virology, pathology, and immunology. This edition features detailed analyses of neuropathogens and syndromes that have emerged in recent years, including human retroviruses, prions, new herpesviruses, a human parvovirus, and diseases caused by zoonotic agents. Two new chapters cover retroviruses and human disease, and extensive material on human immunodeficiency virus has been added to the chapter on infections of the developing nervous system. Dr. Johnson has also added a new chapter on postinfectious syndromes, including virus-induced encephalopathy, Reye syndrome, postpolio syndrome, and chronic fatigue syndrome. This edition provides greater coverage of viruses indigenous to Asia, Africa, and Latin America and examines the threat of these viruses' global spread

目次

  • Part 1 General principles: historical background
  • viruses and virus-cell interactions - nature of viruses, virus-cell interactions, virus-virus interations, effects of virus, replication of cells
  • pathogenesis of CNS infections - experimental approaches, entry of viruses, pathways of neurinvasion, neurotropism, neurovirulence
  • immune responses - anatomy of the immune system, immune responses to viruses, immune responses in the CNS, virus clearance from the CNS. Part 2 Acute neurological diseases: meningitis, encephalitis and poliomyelitis - general considerations, enteroviruses, mumps, adenoviruses, parvovirus, arenaviruses, filoviruses, arbviruses, differential diagnosis
  • herpesvirus infections - varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, human herpesviruses 6 and 7
  • rabies
  • postinfectious demyelinating diseases - considerations of mechanisms, postinfectious enecphalomyelitis, Guillan-Barre syndrome
  • other postviral syndromes - virus-induced encephalopahty, Reye syndrome, postpolio syndrome, chronic fatigue syndrome. Part 3 Chronic neurological diseases: chronic inflammatory and demyelinating diseases - mechanisms of virus persistence in the CNS, subacute sclerosing panencephalitis, progressive rubella panencephalitis, progresive multifocal leukoencephalopathy, possible viral cause of multiple sclerosis, possible viral cuases of other chronic inflammatory diseases
  • retroviruses - nature of retroviruses, human T-cell lymphotrophic viruses, neurological diseases of animal retroviruses
  • human immunodeficiency virus - human immunodeficinecy virus infections, neurological diseases, pathogenesis of neurological diseases, treatment
  • viral infections of the developing nervous sytems - pathogenesis of foetal infections, foetal and neonatal infections in humans, viral teratogenesis in animals
  • degenerative diseases and prions - scrapie, kuru, Creutzfeld-Jakob disease, bovine spongiform encephalopathy, possible viral causes of human degenerative diseases. Part 4 Other perspectives: cerebal tumours - pathogenesis of cell transformation by viruses, experimental production of cerebal tumous
  • evidence for viruses in human brain tumours
  • neurovirology afield - retinitis, labyrinthitis, myositis, vasculitis
  • prevention and treatment - environmental control, vaccines, antiviral drugs
  • postscripts - in defense of the white mouse, Koch's postulates revisited, emerging viral infections.

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