Crystallization of biological macromolecules
著者
書誌事項
Crystallization of biological macromolecules
Cold Spring Harbor Laboratory Press, c1999
- : pbk
大学図書館所蔵 件 / 全27件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references (p. 525-569) and index
内容説明・目次
- 巻冊次
-
ISBN 9780879695279
内容説明
Crystals of macromolecules have become keystones of molecular biology, bridging recombinant DNA and X-ray diffraction analysis. Protein, nucleic acid and virus crystal growth are now possible, raising hopes that virtually all macromolecules might be studied in this way. This work provides a biochemical context in which crystal growth can be pursued and instructs readers in practical aspects of the technology, laying out effective strategies for success. The underlying physical and chemical principles are presented and advances are described.
目次
- The history and character of macromolecular crystals
- principles of macromolecular structure and the applications of X-ray crystallography
- the purification and characterization of biological macromolecules
- some physical and energetic principles
- practical procedures for macromolecular crystallization
- important considerations in macromolecular crystallization
- strategies and special approaches in growing crystals
- impurities, defects and crystal quality
- the mechanisms and energetics of macromolecular crystal growth
- crystal growth in unique environments.
- 巻冊次
-
: pbk ISBN 9780879696177
内容説明
Crystals of macromolecules have become keystones of molecular biology, bridging recombinant DNA and X-ray diffraction analysis. Protein, nucleic acid, and virus crystal growth are now possible, raising hopes that virtually all macromolecules might be studied in this way. This extensively illustrated book, provides a biochemical context in which crystal growth can be pursued and instructs readers in practical aspects of the technology, laying out effective strategies for success. The underlying physical and chemical principles are presented in approachable form and the most recent advances are described, those that have succeeded in transforming the growth of macromolecular crystals from a "black art" to a firmly founded science. This volume should be of interest to investigators in biomedicine whose studies may require a shift in focus from gene to protein product, as well as chemists and physicists interested in the function of biologically active macromolecules.
目次
- The history and character of macromolecular crystals
- principles of macromolecular structure and the applications of x-ray crystallography
- the purification and characterization of biological macromolecules
- some physical and energetic principles
- practical procedures for macromolecular crystallization
- important considerations in macromolecular crystallization
- strategies and special approaches in growing crystals
- impurities, defects, and crystal quality
- the mechanisms and kinetics of macromolecular crystal growth
- crystal growth in unique environments.
「Nielsen BookData」 より