Redirection of Th1 and Th2 responses

Author(s)

    • Coffman, R. L.
    • Romagnani, S.

Bibliographic Information

Redirection of Th1 and Th2 responses

edited by R. L. Coffman and S. Romagnani

(Current topics in microbiology and immunology, 238)

Springer-Verlag, c1999

Available at  / 13 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.

Table of Contents

List of Contents.- The Stability and Reversibility of Th1 and Th2 Populations.- T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases.- Redirecting Th2 Responses in Allergy.- Interleukin-12: Basic Principles and Clinical Applications.- Redirecting Th1 and Th2 Responses in Autoimmune Disease.- Manipulation of Th Responses by Oral Tolerance.

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    Available at 22 libraries

Details

  • NCID
    BA3935162X
  • ISBN
    • 3540650482
  • Country Code
    gw
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Berlin ; Tokyo
  • Pages/Volumes
    vi, 148 p.
  • Size
    24 cm
  • Parent Bibliography ID
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