Redirection of Th1 and Th2 responses
著者
書誌事項
Redirection of Th1 and Th2 responses
（Current topics in microbiology and immunology, 238）
Springer-Verlag, c1999
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
目次
List of Contents.- The Stability and Reversibility of Th1 and Th2 Populations.- T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases.- Redirecting Th2 Responses in Allergy.- Interleukin-12: Basic Principles and Clinical Applications.- Redirecting Th1 and Th2 Responses in Autoimmune Disease.- Manipulation of Th Responses by Oral Tolerance.
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