Malaria : parasite biology, pathogenesis, and protection

著者

• Sherman, Irwin W.

書誌事項

Malaria : parasite biology, pathogenesis, and protection

edited by Irwin W. Sherman

ASM Press, c1998

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Every 30 seconds a death is caused by Malaria. This book brings together recent advances in our understanding of the basic biology, genetics and pathogenesis of malaria, to facilitate the rapid generation of new insights and

目次

• A Brief History of Malaria and Discovery of the Parasite's Life Cycle
• The Current Global Malaria Situation
• Gametocytes and Sexual Development
• Sporogonic Development in the Mosquito
• Engineering Resistance to Malaria Parasite Development in Mosquitoes
• Invasion of Vertebrate Cells: Hepatocytes
• Invasion of Vertebrate Cells: Erythrocytes
• Ultrastructure of Asexual Stages
• Carbohydrate Metabolism of Asexual Stages
• Hemoglobin Processing and the Metabolism of Amino Acids, Heme and Iron
• Malarial Lipids
• Purine and Pyrimidine Metabolism of Asexual Stages
• Malaria Parasite DNA
• The Plasmodium rRNA Genes
• Membrane Transport in the Malaria-Infected Erythrocyte
• The Genetic Structure of Malaria Parasite Populations
• Genome Discovery and Malaria Research: Current Status and Promise
• Extrachromosomal DNA: the Mitochondrion
• Extrachromosomal DNA: Plastid DNA
• Evolutionary Relationships of Human Malaria Parasites
• Introduction to the Modes of Action of and Mechanisms of Resistance to Anitmalarials
• The Molecular Basis of Resistance to the Sulfones, Sulfamides, and Dihydrofolate Reductase Inhibitors
• Chloroquine: Modes of Actions and Resistance and the Activity of Chloroquine Analogs
• From Quinine to Qinghaosu: Historical Perspectives
• Mitochondrial Physiology as a Target for Atovaquone and Other Antimalarials
• Malaria Pathophysiology
• Rosetting of Malaria-Infected Erythrocytes
• Animal Models: Rodents
• Animal Models: Primates
• Host Genetic Factors in Resistance to Malaria
• Acquired Immunity to Sexual Stages
• Acquired Immunity to Asexual Blood Stages
• Acquired Immunity to Sporozoites
• Immunity to Liver Stages
• Using DNA-Based Vaccine Technology and the Malaria Genome Project to Overcome Obstacles to Malaria Vaccine Development.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA39763230
• ISBN:
  • 1555811310
• LCCN: 98008261
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Washington, D.C.
• ページ数/冊数: xiii, 575 p.
• 大きさ: 29 cm
• 分類:
  • LCC : RC156
  • DC21 : 616.9/362
• 件名:
  • LCSH : Malaria
  • LCSH : Plasmodium falciparum