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2004 ISBN 9783540207146
内容説明
The yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Sepsis Mediators.- Cellular Alterations in Sepsis.- Nitric Oxide Metabolism.- Relative Adrenal Insufficiency.- Resuscitation.- Sepsis Therapies.- Additional Therapeutic Agents.- Antimicrobial Strategies.- Respiratory Failure: Basic Mechanisms.- Respiratory Failure: Clinical Aspects.- Mechanical Ventilation.- VILI, VALI, and VASI.- ALI/ARDS.- Abdominal Crises.- Monitoring & Research Techniques.- Ultrasound Techniques.- Oxygen Availability.- Preload Responsiveness.- Fluid Replacement.- Anemia and Oxygen Carriers.- Brain Injury.- Induced Hypothermia.- Comfort in the ICU.- Cost-effectiveness.- Subject Index.
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2005 ISBN 9783540234760
内容説明
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Respiratory Failure. COPD Exacerbations: The Role of Invasive Mechanical Ventilation. Acute Respiratory Failure after Abdominal Surgery. Tracheostomy in Critically Ill Patients: The Right Technique in the Right Patient. Percutaneous Tracheostomy: Past, Present, and Future Perspectives.- Acute Lung Injury. Role of Inducible Nitric Oxide Synthase-derived Excessive Nitric Oxide in the Pathogenesis of Acute Lung Injury. Ischemia-reperfusion Injury of the Lung: Role of Surfactant. Biomarkers for Pulmonary Injury in Critically Ill Patients. Pharmacology of Acute Lung Injury. The Mechanism of Ventilator Induced Lung Injury: Role of Dynamic Alveolar Mechanics. Ventilation-perfusion Distribution Analysis to Assess Ventilatory Modes. Modulators of Ventilator-induced Lung Injury. Assessment of Alveolar Recruitment: New Approaches. Lung Biopsy in ARDS.- Cardiac Crises. The Critically Ill Cardiac Surgery Patient: How to Avoid Postoperative Catastrophe? B-Type Natriuretic Peptide to Assess Cardiac Function in the Critically Ill. Management of Acute Myocardial Infarction. Quantifying Cardiac Dyssynchrony in Man. Diastolic Heart Failure and Critical Illness. Severe Heart Failure in the ICU. Weaning-induced Cardiac Dysfunction. Venous Ultrasonography in Medical Intensive Care.- Circulatory Shock. Resuscitation from Circulatory Shock: An Approach Based on Oxygen-Derived Parameters. Is There a Place for Epinephrine in the Management of Septic Shock?- Resuscitation. New Options for Pharmacological Management of Cardiac Resuscitation. Cardiopulmonary Resuscitation Instructions Provided by Emergency Medical Dispatchers. Thrombolytic Therapy During Cardiopulmonary Resuscitation. Suspended Animation for Delayed Resuscitation.- Intraabdominal Pressure. The Abdominal Compartment Syndrome in the Critically Ill Patient. Non-invasive Modulation of Intraabdominal Pressure.- Severe Infections.< Rational Use of Antibiotics in the ICU: Optimum Efficacy for the Lowest Costs. Pharmacokinetics of Antibiotics During Continuous Renal Replacement Therapy. Impact of Methicillin Resistance on the Outcome of Severe Staphylococcus aureus Infections. Clostridium difficile-associated Disease.- Sepsis and MOF: Basic Mechanisms. The TREMs: A Multifaceted Family of Immunoreceptors. Role of Mannose-Binding Lectin in Host Defense. Mitochondrial Dysfunction in Sepsis: Where Are We Now? Localized Coagulation Activation and Fibrin Deposition in Critically Ill Patients. The Central and Autonomic Nervous System: Essential Regulators of the Immune Response.- Sepsis: Clinical Aspects. Severe Sepsis in the Elderly. Extravascular Lung Water in Sepsis. Procalcitonin on the Dusty Way to the Holy Grail: A Progress Report. Statins in Critical Illness.- Blood Transfusions. Anemia in Critically Ill Patients. Pathophysiology, Benefits, and Risks of Red Blood Cell Transfusion.- The Microvasculature. The Microcirculation During Wound Healing after Oral Maxillofacial Surgical Procedures. Modulation of Microcirculatory Disorders by Coagulatory Inhibitors. Sublingual Capnometry in Pediatric Patients.- Cardiorespiratory Monitoring. New Echocardiographic Parameters of Fluid Responsiveness in Ventilated Patients. Echo and PiCCO: Friends or Foe? Lithium Dilution Cardiac Output and Arterial Pulse Power Analysis (LIDCOTM plus System). Mixed and Central Venous Oxygen Saturation. Cost-Effectiveness of Minimally Invasive Hemodynamic Monitoring. Gas Exchange Measurement in the ICU: State of the Art and Potential Future Applications.- Neurologic Crisis. Management of Large Hemispheric Infarction. Inducing Hypothermia in the ICU: Practical Aspects and Cooling Methods.- Metabolic Alterations. Making Strong Ion Difference the "Euro" for Bedside Acid-Base Analysis. Plasma High Volume Hemofiltration: Rationale and Early Clinical Experience. Liver Transplantation in The Management of Fulminant Hepatic Failure.- Sedation. Sedation Strategies in the Critically Ill. Delirium in the Intensive Care Unit.- Quality Issues. The Critically Ill Obese Patient: A Management Challenge. Computers in the ICU: Fasten your Seatbelts!. Reducing ICU Mortality: To What Extent? Improving Palliative Care for Patients in the Intensive Care Unit.
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2006 ISBN 9783540301554
内容説明
The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Cellular Responses in Sepsis.- The Role of Toll-like Receptors in Sepsis.- The Emerging Role of RAGE in Sepsis.- Oxidative Stress in Sepsis: Implications on Liver Protein Patterns and Analysis via Modified Proteomics Technology.- HSP90: The Unsung Villain of Sepsis?.- The Role of Extracellular Heat Shock Proteins in Cellular Inflammation and Injury.- Quantitative in vivo Protein Synthesis as a Measure of Immune Function.- Fluid Resuscitation and Immunomodulation in the Critically III.- Cellular Dysfunction.- Mitochondrial Dysfunction and Critical Illness Myopathy.- Lactic Acidosis and Hyperlactatemia.- Cardiovascular Dysfunction.- Physiology and Pathophysiology of the Natriuretic Peptide System.- Heart Failure as a Co-Morbidity in the ICU.- The Vascular Bed during Critical Illness: Evaluation in Animal Models.- Hemodynamic Monitoring.- Intensive Care Echocardiography.- Intrathoracic Blood Volume: Clinical Applications.- Hemodynamic Management Guided by Esophageal Doppler.- Less Invasive Cardiac Output Monitoring: Characteristics and Limitations.- Pulse Pressure Analysis.- Pulse Pressure Variations in Managing Fluid Requirement: Beware the Pitfalls!.- Minimally Invasive Hemodynamic Monitoring Using the Pressure Recording Analytical Method.- Coagulopathies.- Thrombotic Microangiopathy Syndrome in the ICU.- Altered Functionality of von Willebrand Factor in Sepsis and Thrombocytopenia - Potential Role of the vWF Cleaving Protease ADAMTS-13.- Coagulopathy in the Critically Injured Patient.- Critical Bleeding in Blunt Trauma Patients.- Trauma: Bleeding, Coagulopathy, and Blood Component Transfusion.- Hemostatic Resuscitation.- Effects of Plasma Substitutes on Coagulation.- Blood Transfusions.- Transfusion as a Risk Factor for ALI and ARDS.- Red Blood Cell Desialylation in Critically III Patients: An Underestimated Cause of Anemia.- Cardiopulmonary Resuscitation.- Clinical Predictors of Physiological Deterioration and Subsequent Cardiorespiratory Arrest among Hospitalized Patients.- Cardiocerebral Resuscitation: A Better Approach to Out-of-Hospital Cardiac Arrest.- Induced Hypothermia for Neuroprotection: Understanding the Underlying Mechanisms.- Acute Lung Injury.- Hyaluronan in Acute Lung Injury.- Aspiration-induced Lung Injury: Experimental and Human Studies.- Pulmonary Edema in Organ Donors and Lung Transplant Recipients: Is there a Role for Beta-adrenergic Agonists?.- Respiratory Support.- Current Concepts of Airway Management in the ICU and the Emergency Department.- Use of Continuous Positive Airway Pressure in Critically Ill Patients.- Non-invasive Respiratory Support in Pre-term Neonates and Pediatric Patients with Respiratory Failure.- Fast and Slow Compliance: Time, in Addition to Pressure and Volume, is a Key Factor for Lung Mechanics.- Does Ventilator-Induced Lung Injury Initiate Non-Pulmonary Organ Dysfunction?.- Monitoring in Respiratory Failure.- Electrical Impedance Tomography and its Perspectives in Intensive Care Medicine.- Electrical Impedance Tomography for Monitoring of Regional Ventilation in Critically III Patients.- Volumetric Capnography for Monitoring Lung Function During Mechanical Ventilation.- Monitoring Respiratory Drive and Respiratory Muscle Unloading During Mechanical Ventilation.- Weaning from Mechanical Ventilation.- Weaning from Mechanical Ventilation.- Liberation from Mechanical Ventilation in Acutely Brain-injured Patients.- Non-invasive Ventilation for Respiratory Failure after Extubation.- Burn Injury.- Importance of Airway Management in Burn and Smoke Inhalation-induced Acute Lung Injury.- Metabolic Changes Following Major Burn Injury: How to Improve Outcome.- Antibiotic Dosing in Burn Injury: Should We be Looking at the Tissues more Closely?.- Metabolic Support.- Defining Relative Adrenal Insufficiency in the Critically III: The ACTH Test Revisited.- Enteral Nutrition in the Critically III: Should We Feed into the Small Bowel?.- Tight Energy Balance Control for Preventing Complications in the ICU.- Bacteriological Problems.- Acute Pneumonia and Importance of Atypical Bacteria.- Antibiodic Resistance in the Intensive Care Unit.- Fungal Infections.- Systemic Candida Infection in the ICU.- Candida Colonization Index in the Management of Critically III Patients.- Antifungal Therapy in Surgical ICU Patients.- Hepatosplanchnic Failure.- Splanchnic Perfusion and Oxygenation in Critical Illness.- Liver Failure: Diagnostic Assessment and Therapeutic Options.- Immunoparalysis in Liver Disease.- Hepatorenal Syndrome.- Renal Failure.- Sepsis and Acute Renal Failure.- Sixty Years of 'Extended Dialysis' in the ICU.- Anticoagulation in CRRT: Systemic or Regional?.- Plasma Filtration Adsorption Dialysis: A New Experimental Approach to Treatment of Sepsis and MOF.- Sleep and Delirium.- Sleep in the ICU.- Sleep and Delirium in the Critically Ill: Cause or Effect?.- Delirium, Recall and the Post-ICU Challenge.- Contemporary Issues.- Morbid Obesity as a Determinant of Outcome in the Critically Ill.- Patient Safety Management System in Pediatric ICUs.- Information Exchange in Intensive Care: How can we Improve?.- Catastrophic Anachronisms: The Past, Present and Future of Disaster Medicine.- Health Services Research and Critical Care.- Healthcare Disparities in Critically Ill Patients.- International Comparisons of Intensive Care: Understanding the Differences.
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2002 ISBN 9783540431497
内容説明
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Cellular Responses.- Ischemia-reperfusion and Acute Apoptotic Cell Death.- Alpha-4 Integrin: A Novel Mechanism for Neutrophil-endothelial Interaction.- Cell Adhesion Molecules and Leukocyte Trafficking in Sepsis.- Molecular Mechanisms of Complement Activation during Ischemia and Reperfusion.- Gender and Cell-mediated Immunity following Trauma, Shock, and Sepsis.- Bask Mechanisms in Acute Respiratory Failure.- Regulatory Role of Alveolar Macrophages and Cytokines in Pulmonary Host Defense.- Apoptosis in Pneumonia.- Hypoxic Pulmonary Vasoconstriction and the Pulmonary Microcirculation.- Pulmonary Endothelial Angiotensin Converting Enzyme Activity in Lung Injury.- Modulating Host Response.- Antioxidants and Endothelial Function: Therapeutic Implications.- Pentoxifylline: A Useful Adjuvant in the Critically Ill?.- High Volume Hemofiltration in Sepsis.- Adjuvant Treatment of Mediastinitis with Immunoglobulins after Cardiac Surgery: The ATMI Trial.- The Immunomodulatory Effects of Anesthetic and Analgesic Agents.- Myocardial Responses.- Myocardial Ischemia-reperfusion Injury: Role of the Peroxynitrite-poly(ADP-ribose) Polymerase Pathway.- Effects of Anesthetics on Ischemia-reperfusion Injury of the Heart.- Regulatory Role of Nitric Oxide in the Heart of the Critically Ill Patient.- TNF as a Mediator of Cardiac Depression following Snakebite.- Acute Right Ventricular Failure: Physiology and Therapy.- Cardiovascular Management.- The Rationale for Vasodilator Therapy in Sepsis.- Vasopressin and its Analogs.- Mechanical Ventilation.- The Use of Ventilatory Modes allowing Spontaneous Breathing during Mechanical Ventilation.- Neural Control of Mechanical Ventilation: A New Approach to Improve Patient-Ventilator Interaction.- Assisting Ventilation by Pressure Support: More than a Weaning Tool.- Conditioning of Inspired Gases in Mechanically Ventilated Patients.- Bronchodilator Therapy in Mechanically Ventilated Patients.- Management of Acute Respiratory Failure.- Titrating Optimal PEEP at the Bedside.- Effect of PEEP and Targets During Mechanical Ventilation in ARDS.- Lung Recruitment in Localized Lung Injury.- Advances in ARDS: How do they Impact Bedside Management?.- Non-invasive Mechanical Ventilation.- Methodology of Non-invasive Mechanical Ventilation in Acute Respiratory Failure.- Non-invasive Mechanical Ventilation and Prevention of Pneumonia in Patients with Acute Respiratory Failure.- Infectious Challenges.- Evaluation of Non-responding Patients with Ventilator-associated Pneumonia.- The Prevention of Invasive Candida Infection in Critically Ill Surgical Patients.- Bacterial CpG DNA in Septic Shock.- Antibiotics by Continuous Infusion: Time for Re-evaluation?.- Extended Spectrum Beta-lactamases in Gram-negative Sepsis.- Fluid Therapy.- Towards Safer Central Venous Access.- Strong Ions, Acid-base, and Crystalloid Design.- Reactive Oxygen Species as Mediators of Organ Dysfunction: Potential Benefits of Resuscitation with Ringer's Ethyl Pyruvate Solution.- The Immunological Effects of Hypertonic Saline.- Does Albumin Infusion Affect Survival? Review of Meta-analytic Findings.- Metabolie Support.- Lipids in Parenteral Nutrition: Benefits in Critically Ill Patients?.- Early Enteral Nutrition in the Intensive Care Unit.- Relative Adrenal Insufficiency Syndrome.- Metabolic Effects of Adrenergic Drugs.- Acidemia: Good, Bad, or Inconsequential?.- Cardiorespiratory Monitoring.- Monitoring Left Heart Performance in the Critically Ill.- Functional Hemodynamic Monitoring: Applied Physiology at the Bedside.- Detection of Fluid Responsiveness.- Volumetric Capnography in the Non-intubated Critically Ill Patient.- Assessment of Lung Function in Mechanically Ventilated Patients.- Tissue Lactate Concentrations in Critical Illness.- Oxygen Delivery.- Oxygen Delivery and the Critically Ill.- Monitoring Intensive Care Patients.- Gastric Mucosal Tonometry in Daily ICU Practice.- Coagulopathies.- Thrombotic Microangiopathies.- Pro-hemostatic Therapy for Prevention and Treatment of Bleeding.- Coagulopathy in Trauma Patients.- Head Trauma.- Traumatic Brain Injury: Severity and Outcome.- Biochemical and Molecular Mechanisms after Severe Traumatic Brain Injury in Children.- Monitoring of Intracranial Pressure and Cerebral Compliance.- The MRC CRASH Trial.- Neurological Challenges.- Assessing Consciousness in Critically Ill Patients.- The Brain in Post-anoxic Coma: Predicting Outcome.- The Rationale for Human Selective Brain Cooling.- Septic Encephalopathy.- Critical Care Management of Refractory Status Epilepticus.- Neurocognitive Impairment in Survivors of ARDS.- Abdominal Crises.- Immunomodulatory Treatment of Severe Acute Pancreatitis.- Abdominal Perfusion Pressure as a Prognostic Marker in Intra-abdominal Hypertension.- Intra-abdominal Pressure and Chest Wall Interaction.- Renal Failure.- The Kidney in Sepsis.- Hepatorenal Failure.- Acute Renal Failure in the Critically Ill Patient: Is there a Magic Bullet?.- Particular Aspects.- Perioperative Management of the Severely Burned Patient.- Hypertensive Crises.- Cardiac Arrest in Children.- The Etiology of Obstetric Critical Illness.- Severity of Illness.- Measuring Organ Dysfunction.- Severity of Illness Scoring Systems.- Quality of Care.- Discharging the Critically Ill Patient.- Patient Examination in the Intensive Care Unit.- Are Autopsies still Useful in the Intensive Care Unit?.
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2003 ISBN 9783540443827
内容説明
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Epithelial-Endothelial Alterations.- Sepsis: Mechanisms and Therapy.- Coagulation Abnormalities.- Infectious Challenges.- Acute Respiratory Failure.- Ventilatory Support.- Inhalation Therapies.- Perioperative Complications.- Cardiac Crises.- Cardiopulmonary Resuscitation.- Monitoring Systems.- Oxygen Availability.- Fluid Therapy.- Renal Failure.- Brain-Lung Interactions.- Neurological Crises.- Emergency Medicine.- GI Crises.- Metabolic Support.- Management, Education, and Ethics.- Subject Index.
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2007 ISBN 9783540494324
内容説明
The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Biomarkers.- Sepsis and Infection: Management.- Severe Lung Infections.- Mechanisms of Organ Dysfunction.- Lipids.- Acute Lung Injury.- Mechanical Ventilation.- Protective Ventilation in Respiratory Failure.- Cardiovascular Topics.- Hemodynamic Monitoring.- Intravenous Fluid Therapy.- Renal Failure.- Abdominal Pathologies.- The Liver.- Neurological Issues.- Management of Burns.- Hematological Alterations.- Does Sex Make a Difference?.- Prognosis and Long-term Outcomes.- Quality and Management.- Disasters.
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1998 ISBN 9783540637981
内容説明
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in their field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediattrics, intensive care and emergency medicine. (With approximately 90 contributions.)
目次
Host Responses in Sepsis and ARDS.- Balancing the Inflammatory Response in Sepsis.- Bactericidal/Permeability-Increasing Protein (BPI): Structure, Function, and Clinical Applications.- Inhibition of the Activation of Nuclear Factor-?B as a Novel Therapeutic Approach for SIRS and Septic Shock.- The Role of the Host Defense Response in the Progression and Outcome of ARDS.- The Role of Cytokines in the Pathogenesis of Pneumonia.- A Central Role of Interleukin-8 in the Pathogenesis of ARDS.- Neutrophil Myeloperoxidase: Effector of Host Defense and Host Damage.- NAD(P)H Oxidase in Non-Phagocytic Cells.- Gelatinases and Acute Respiratory Distress Syndrome.- Cardiocirculatory Alterations.- Molecular Mechanisms of Action of Nitric Oxide in Heart Muscle.- Development of Myocardial Tolerance to Ischemia/Reperfusion and Septic Injury.- Endothelial Cell Dysfunction in Septic Shock.- Alterations of Important Regulators of Macro-and Microcirculation in the Critically Ill.- Microvascular Regulation of Tissue Oxygenation in Sepsis.- Selective Pharmacological Inhibition of Inducible Nitric Oxide Synthase in Experimental Septic Shock.- The Use of Dopamine and Norepinephrine in the ICU.- Oxygen Carriers.- The Red Blood Cell: New Ideas About an Old Friend.- Transfusion Requirements in Critical Care: A Multicenter Controlled Clinical Trial.- Artificial Oxygen Carriers.- Epidemiology and Markers of Sepsis - Clinical Trials.- Do We Really Know the Epidemiology and Clinical Course of Sepsis?.- Prognostic Markers in Sepsis.- Procalcitonin - An Indicator of Sepsis.- Is There a Role for Surrogate Markers in the Evaluation of Sepsis Trials.- Discourse on Method: Measuring the Value of New Therapies in Intensive Care.- Severe Infections.- Antimicrobial Therapy for ICU-Acquired Infection: Time for a Reappraisal.- Nosocomial Sinusitis: A Critical Appraisal of the Evidence.- The Importance of Initial Empiric Antibiotic Selection in Ventilator-Associated Pneumonia.- Why, When, and How to Prescribe a Combination of Antibiotics.- Prevention of Infections Associated with Vascular Catheters.- Management of Fever in Cancer Patients with Acquired Neutropenia.- Measuring Lung Mechanics.- Determination of Lung Volume in the ICU.- Chest Wall Mechanics: Methods of Measurement and Physiopathologie Insights.- Modes of Mechanical Ventilation.- Emergency Intubation: The Difficult Airway.- Control of Breathing During Assisted Mechanical Ventilation.- Proportional Assist Ventilation.- Pressure Controlled Ventilation (PCV): The Ideal Mode of Mechanical Ventilation?.- The Open Lung Concept.- Lung Stretching and Barotrauma.- Inflammatory Consequences of High Stretch Lung Injury.- Mechanical Ventilation-Induced Injury.- Barotraumatic Effects of Mechanical Ventilation.- Weaning from Mechanical Ventilation.- The Pathophysiology of Weaning Failure.- What Have We Learned About Weaning Over the Last Five Years.- Non-Invasive Mechanical Ventilation.- Non-Invasive Ventilation in Acute Respiratory Failure: Technological Issues.- Non-Invasive Nocturnal Mechanical Ventilation: Is it Feasible for COPD Patients?.- Lung Perfusion - Inhaled Nitric Oxide.- Distribution of Pulmonary Perfusion in Healthy and Injured Lungs.- The Administration and Measurement of Nitric Oxide During Mechanical Ventilation.- Inspiratory Nitric Oxide Concentration Fluctuation During Inhalational NO Administration.- Effects of Inhaled Nitric Oxide on Circulating Blood Cells.- Acid-Base - Lactate Metabolism.- Recent Advances in Acid-Base Physiology Applied to Critical Care.- Pivotal Role of Lactate in Aerobic Energy Metabolism.- Metabolism.- Skeletal Muscle in Critical Illness.- Metabolic Requirements of the Neurosurgical Patient.- Enteral Nutrition in the Critically 111 Patient: A Practical Approach.- Immunonutrition in Cancer Surgical Patients.- The Gut.- Ischemia/Reperfusion of the Gut.- Stress Ulceration in the Critically Ill Population.- Hemodynamic Management of Gastric Intramucosal Acidosis in Septic Patients.- Intra-Abdominal Hypertension and Intensive Care.- Head Trauma.- Pharmacological Augmentation of Endogenous Neuroprotective Responses after Traumatic Brain Injury.- Experimental and Clinical Neuroprotection: An Update.- Cerebral Extraction Monitoring in Brain Injury.- Surgery and Obstetrics.- Pediatric Problems in Heart Surgery.- Crises in Pre-Eclampsia.- ICU Performance - Evaluation.- Performance of the ICU: Are We Able to Measure it?.- Evidence-Based Medicine: The Wolf in Sheep's Clothing.
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1999 ISBN 9783540652885
内容説明
A compilation of the most recent and widespread developments in experimental and clinical research and practice -- all in one comprehensive reference. Around 90 contributions, written by recognized experts in intensive care and emergency medicine, will be of interest to everyone involved in internal medicine, anesthesia, surgery, pediatrics, as well as intensive care and emergency medicine.
目次
Predisposition to Critical Illness.- Prevention of Critical Illness: Determinants of Risk.- Pro-Inflammatory Cytokine Genomic Polymorphism and Critical Illness.- Immunologic Responses.- Bacterial Modulation of the Immune Response to Infection and its Consequences.- Treating Immunologic Instability: A Change in Focus.- Interleukin-6 in Bacterial Infection and Sepsis: Innocent Bystander or Essential Mediator?.- Complement Activation by C-Reactive Protein: An Inflammatory Mechanism in Human Disease?.- Influence of Nutrition on Mucosal Immunity.- Metabolic Support.- Studies of Protein and Amino Acid Metabolism in the Human Liver.- Anabolic Strategy in ICU Patients: Is there a Place for Growth Hormone?.- Controversies in Nutrition of the Critically Ill.- The Hemodynamic Response to Enteral Nutrition.- Infectious Challenges.- Clinical Significance of Antimicrobial Resistance.- Colonization and Infection with Pseudomonas aeruginosa in Intensive Care: Endogenous or Exogenous Origin?.- Severe Pneumonia in the Elderly.- The Role of Pulmonary Bacterial Infections in Severe Exacerbations of COPD Patients.- Treatment of Septic Shock.- Volume Kinetics: A New Method to Optimize Fluid Therapy.- Why, When, and How I Use Norepinephrine in the Treatment of Septic Shock.- Stress Doses of Hydrocortisone in Septic Shock: Beyond the Hemodynamic Effects.- Altered Respiratory Function.- Breathing Pattern of Patients with COPD.- Lung Mechanics in ARDS.- Mechanical Ventilation.- The Laryngeal Mask in Emergency Medicine and Intensive Care Medicine.- Improving Patient/Ventilator Interactions.- Beneficial Effects of Helium-Oxygen Mixtures in Acute Respiratory Failure.- Mechanisms of Regional Lung Expansion in Acute Respiratory Distress Syndrome.- Lung Protection during Mechanical Ventilation.- Neuromuscular Failure.- Diagnosing Respiratory Muscle Weakness.- Interaction of Respiratory Muscles and Circulation in Heart Failure.- Assessment of Respiratory and Limb Muscle Function in the Intensive Care Unit.- Risk Factors for Polyneuromyopathy of Critical Illness.- Neurologic Problems.- Emergency Treatment and Intensive Care in Ischemic Stroke.- Intensive Care Management of Aneurysmal Subarachnoid Hemorrhage.- Magnetic Resonance Spectroscopy and Neurotrauma.- Cell Oxygenation.- Coping with Hypoxia.- Intracellular Signaling by Reactive Oxygen Species during Hypoxia.- Heme Oxygenase and Acute Lung Injury: The Functional Significance of Heme Oxygenase Induction.- Protective Role of Inhaled Nitric Oxide in Ischemia/Reperfusion and Endotoxin-Induced Inflammation.- Oxygen Delivery.- Oxygen Therapy in Intensive Care Patients: A Vital Poison?.- The Significance of the P50.- The Red Blood Cell and Nitric Oxide.- Cardiovascular Monitoring.- Continuous Arterial Thermodilution Cardiac Output and Derived Variables.- Transesophageal Eunncardiographic Evaluation of Left Ventricular function.- The Esophageal Doppier.- Cardiovascular Alterations.- Myocardial Inducible Nitric Oxide Synthase and Left Ventricular Performance in the Human Heart.- Alteration of the Beta-Adrenergic Pathway in the Septic Heart.- Autonomic Dysfunction in Critically Ill Patients.- Gut Ischemia.- The Role of the Gut in Multiple Organ Failure.- Gastric Intramucosal Acidosis, pHi and the Tonometer: What is the Benefit for Patients?.- Coagulation Abnormalities.- Hemolytic Uremic Syndrome/Thrombotic Thrombocytopenic Purpura in the ICU.- Point-Of-Care Monitoring of Coagulation in the Critically Ill.- Peri-Operative Complications.- Peri-Operative Risk Factors for Post-Operative Pulmonary Complications.- Rationale Behind "Off Pump" Coronary Surgery: Why Patients Tolerate it Better?.- Renal Support.- The History of Continuous Renal Replacement Techniques.- Continuous Renal Replacement Therapies in Sepsis: Do they Matter?.- Drug Addiction.- Drugs of Abuse in the Intensive Care Unit Setting.- Ecstasy (MDMA): An Update.- Rapid Opiate Detoxification Under General Anesthesia: A New Challenge for Anesthesiologists and Intensivists.- Economics and Ethics.- Survival is not Enough: Quality of Life After Intensive Care.- Economic Perspectives on Intensive Care Medicine.- Health Economics in Intensive Care.- Ethical Implications of Standardizing Clinical Decisions with Computerized Protocols.- Medical Futility in the New Millennium: Our View.
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2000 ISBN 9783540668305
内容説明
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in their field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine. (With approximately 90 contributions.)
目次
Sepsis and Inflammation.- The Molecular Genetics of Sepsis: Clinical Epidemiology Considerations.- The Role of Interleukin (IL)-12 and IL-18 During Endotoxemia and Bacterial Infection.- The Apoptotic Response of the Lymphoid Immune System to Trauma, Shock, and Sepsis.- Modulation of Neutrophil Function in Sepsis.- Trauma-Induced Immunosuppression: Pathogenesis and Treatment.- The Influence of Nutrition on Mucosal Immunology and Endothelial Cell Adhesion Molecules.- Intestinal Microcirculation: Changes in Sepsis and Effect of Vasoactive Manipulation.- Microvascular Permeability in Experimental Sepsis: Mechanisms, Modulation and Management.- Infectious Challenges.- Catheter-Related Infections in the ICU.- Ecological Impact of Beta-lactam Treatment on Normal Human Intestinal Microflora.- Non-Pharmacologic Prevention of Ventilator-Associated Pneumonia (VAP).- Fungal Infections.- Fungal Infections in Critically Ill Surgical Patients.- Candida: Some Thoughts.- Steroid Therapy.- Clinical Impact of Glucocorticoid Pharmacodynamics.- Corticosteroids in the Acute Respiratory Distress Syndrome.- Corticosteroid Therapy in Critical Illness: A Changing Paradigm.- Pathophysiology of Lung Injury.- Alveolar Epithelial Barrier: Acute Lung Injury.- Pulmonary Oxygen Toxicity in Man: Emerging Concepts in Pathogenesis and Prevention.- Fibrosis in ARDS: How Close is the Link between Inflammation and Fibroproliferation?.- The Clinical Relevance of Exhaled Nitric Oxide: A Critical Review.- Acute Respiratory Failure.- Hypoxemia and Mortality in the ICU.- Diffuse Alveolar Hemorrhage in the ICU.- Optimal Positioning for the Adult Intensive Care Patient while Prone.- Mechanical Ventilation.- Utilization of Mechanical Ventilation in Critical Care.- Respiratory Physiology as a Basis for the Management of Acute Lung Injury.- High Frequency Oscillatory Ventilation: A Tool to Decrease Ventilator-Induced Lung Injury?.- Extubation Failure.- Non-invasive Ventilation: Why Does It Fail?.- Surgery.- Reducing the Morbidity and Mortality of High-Risk Surgical Patients.- Causes of Oxygenation Impairment During Anesthesia.- Respiratory Function in Obese Patients in the Peri-operative Period.- Post-operative Myocardial Ischemia and Infarction.- Abdominal Crises.- Novel Strategies for the Management of Severe Acute Pancreatitis.- The Hepatorenal Syndrome.- Sedation.- Sedation in the Intensive Care Environment.- Intensive Care Sedation: The Alpha-2 Agonists.- Intravenous Fluids.- Fluid Therapy: Present Controversies.- Crystalloids versus Colloids in the Treatment of Hypovolemic Shock.- Human Albumin on the ICU: Can We Live Without It?.- Intra-operative Use of Hypertonic Solutions.- Adverse Effects of Colloids on Renal Function.- Should Old Red Cells be Transfused in Critically Ill Patients?.- Current Status of Artificial Oxygen Carriers.- Emergencies.- Intensive Care in a Forward Deployed Military Field Surgical Combat Support Hospital.- Diagnosis of Traumatic Aortic Injuries.- Diagnosis and Treatment of Hyperosmolar Emergencies.- Neurology.- Conservative and Invasive Treatment of Space-Occupying Hemispheric Stroke.- Thrombolytic Therapy for Intraventricular and Intraparenchymal Hemorrhage.- Cerebral Function in Vegetative State studied by Positron Emission Tomography.- Cardiovascular Crises.- Evaluation of Platelet Membrane Glycoproteins in Ischemic Heart Disease.- Coronary Thrombosis and Myocardial Infarction.- Diagnosis and Treatment of Tachycardias.- Cardiopulmonary Resuscitation: Lessons from the Past and Trends for the Future.- Effects of Catecholamine Therapy on Regional Perfusion in Septic Shock.- ICU Monitoring.- Evaluation of Cardiac Output and Cardiac Preload.- Transesophageal Echocardiography: The Relationship between Pressure, Flow and Function.- Respiratory Changes in Arterial Pressure in Mechanically Ventilated Patients.- The Study of the Microcirculation using Orthogonal Polarization Spectral Imaging.- Assessment of Tissue Oxygenation in the Critically Ill.- Blood Gas Monitoring with Optodes.- Interpretation of Changes in Regional and Mucosal PCO2, Gradients: The Haldane Effect.- The Meaning of Lactate.- Routine Assessment of Tissue Metabolism in the Critically Ill.- ICU Costs.- The Costs of Infection in the ICU.- Costs of Antibiotic Therapy: Maximizing Effectiveness While Minimizing Cost.- Clinical Pathways as a Tool for 'Intelligent' Rationing in Intensive Care.- 2000 and Beyond.- The Constraints and Necessity of Teaching Emergency Medicine to Medical Students.- ICU Organization: Does it Matter?.- Training of Young Intensivists in Management Skills for the New Millennium.- Outcome Prediction in Intensive Care.- Critical Care in the Elderly: The Final Challenge.
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2008 ISBN 9783540772897
目次
Genetic Factors.- Cardiac Issues.- Cardiopulmonary Resuscitation.- Emergencies.- Poisonings.- Acute Respiratory Failure.- Ventilatory Support.- Tracheostomy.- Infections.- Cellular Mechanisms in Sepsis.- Sepsis Therapies.- Metabolic Alterations.- Fluid Management.-Acute Kidney Injury.- Hemodymic Assessment and Management.- Tissue Oxygenation.- Anticoagulants in Organ Failure.- Acute Bleeding.- Hepatic Disease.- Neurological Crises.- Analgesia and Sedation.- Outcomes.
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2009 ISBN 9783540922759
内容説明
This yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
目次
Genomics and Proteomics.- Rethinking Sepsis: New Insights from Gene Expression Profiling Studies.- Mitochondrial Genetics and Sepsis.- Lung Proteomics in Intensive Care.- Inflammatory Response.- The Host Response to Sepsis.- Endotoxin Tolerance:Mechanisms and Clinical Applicability.- Oxidative Stress and Endothelial Dysfunction during Sepsis.- Measurement of Carbon Monoxide: From Bench to Bedside.- Monitoring Immune Dysfunction in Septic Patients: Toward Tailored Immunotherapy.- Current and Future Management of Sepsis.- Source Control in the ICU.- IgM-enriched Immunoglobulins in Sepsis.- Clarithromycin: A Promising Immunomodulator in Sepsis.- High-flow Hemofiltration as an Adjunctive Therapy in Sepsis.- Economic and Social Burden of Severe Sepsis.- Proposed Targets for New Therapies.- Lymphocyte Apoptosis in Sepsis and Potential Anti-apoptotic Strategies.- The Pivotal Role of Beta-adrenoreceptors in Critical Illness Pathophysiology.- Non-septic Acute Lung Injury and Inflammation: Role of TLR4.- Hydrogen Sulfide: A Metabolic Modulator and a Protective Agent in Animal Models of Reperfusion Injury.- Septic Shock.- 'Myocardial Depression' or' Septic Cardiomyopathy'?.- Determinants of Tissue PCO2 in Shock and Sepsis: Relationship to the Microcirculation.- Refining the Tools for Early Goal-directed Therapy in Septic Shock.- Intravenous Fluids.- Hyperchloremic Metabolic Acidosis: More than Just a Simple Dilutional Effect.- Old versus New Starches: What do We Know about their Differences?.- Impact of Hydroxyethyl Starch on Renal Function.- Rational Approach to Fluid Therapy in Acute Diabetic Ketoacidosis.- Hemodynamic Support.- Cardiac Filling Volumes and Pressures in Assessing Preload Responsiveness during Fluid Challenges.- Update on Preload Indexes: More Volume than Pressure.- Monitoring Arterial Blood Pressure and Cardiac Output using Central or Peripheral Arterial Pressure Waveforms.- Intrathoracic Pressure Regulation for the Treatment of Hypotension.- Functional Hemodynamic Monitoring: A Personal Perspective.- Airway Management.- Endotracheal Intubation in the ICU.- Pediatric Advanced Airway Management Training for Non-anesthesia Residents.- Automatic Tube Compensation in the Weaning Process.- Mechanical Ventilation.- Extracorporeal Membrane Oxygenation for Cardiac and Pulmonary Indications: Improving Patient Safety.- Patient-ventilator Interaction during Noninvasive Ventilation.- Variable Mechanical Ventilation: Breaking the Monotony.- Life-threatening Asthma: Focus on Lung Protection.- Respiratory Monitoring.- Bedside Monitoring of Diaphragm Electrical Activity during Mechanical Ventilation.- Electrical Impedance Tomography.- Regional Ventilation Delay Index: Detection of Tidal Recruitment using Electrical Impedance Tomography.- Different Approaches to the Analysis of Volumetric Capnography.- Variation in Extravascular Lung Water in ALI/ARDS Patients using Open Lung Strategy.- Clinical Utility of Extravascular Lung Water Measurements.- Perioperative Management.- Rationalizing the Use of Surgical Critical Care: The Role of Cardiopulmonary Exercise Testing.- Advanced Minimally Invasive Hemodynamic Monitoring of the High-risk Major Surgery Patient.- Post-pneumonectomy Pulmonary Edema.- The Role of Phenylephrine in Perioperative Medicine.- Role of the Calcium Sensitizer, Levosimendan, in Perioperative Intensive Care Medicine.- Inhaled Nitric Oxide Therapy in Adult Cardiac Surgery.- Cardiac Function.- Use of Natriuretic Peptides in the Emergency Department and the ICU.- Abnormalities of the ST Segment.- Functional Mitral Regurgitation in the Critically III.- Cardiopulmonary Resuscitation.- Feedback to Improve the Quality of CPR.- The Post-cardiac Arrest Syndrome.- Use of a Standardized Treatment Protocol for Post-cardiac Resuscitation Care.- Therapeutic Hypothermia after Cardiac Arrest.- Renal Function.- Biomarkers of Acute Kidney Injury in Critical Illness.- The Role of Biomarkers in Cardiac Surgery-associated Acute Kidney Injury.- Neutrophil Gelatinase- associated Lipocalin: An Emerging Biomarker for Angina Renalis.- Hepatosplanchnic Function.- How does Intra-abdominal Pressure Affect the Daily Management of My Patients?.- ICG Clearance Monitoring in ICH Patients.- Acute-on-Chrenic Liver Failure in Cirrhosis: Defining and Managing Organ Dysfunction.- Nutrition.- The Curse of Overfeedinc and the Blight of Underfeeding.- Enterai Feeding during Circulatory Failure: Myths and Reality.- Enterai Nutrition with Anti-inflammatory Lipids in ALI/ARDS.- Glutamine Supplementation in ICU Patients.- Glucose Control.- Burn Causes Prolonged Insulin Resistance and Hyperglycemia.- Glucose Variability in Critically III Patients.- Adrenal Function.- Corticosteroid Biology in Critical Illness: Modulatory Mechanisms and Clinical Implications.- Corticosteroid Treatment of Patients in Septic Shock.- Coagulation.- New Anticoagulants: Anti-lla or Anti-Xa agents?.- Emergency Reversal of Anticoagulants.- Neurological Aspects.- The Role of Imaging in Acute Brain Injury.- Monitoring and Managing Raised Intracranial Pressure after Traumatic Brain Injury.- Sepsis-associated Encephalopathy.- Malignancies.- Acute Tumor Lysis Syndrome: Diagnosis and Management.- Life-threatening Neurological Complications in Patients with Malignancies.- Should We Admit Critically III Cancer Patients to the ICU?.- Drug Dosing.- Optimizing Drug Dosing in the ICU.- Relevant CYP450-mediated Drug Interactions in the ICU.- Sedation and Analgesia.- Sedation and Pain Management in the ICU.- The Role of Dexmedetomidine in Intensite Care.- Monitoring Delirium in the ICU.- ICU Management.- Intensite Care for the Elderly: Current and Future Concerns.- ICU Performance: Managing with Balanced Scorecards.- End-of-Life Issues.- Towards a Neuro-scientific Explanation of Near-death Experiences?.- Managing Conflict at the End-of-Life.- Strengths and Weaknesses of Substitute Decision Making in the ICU.
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2010 ISBN 9783642102851
内容説明
This yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
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