Alzheimer disease
著者
書誌事項
Alzheimer disease
Lippincott Williams & Wilkins, c1999
2nd ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The Second Edition of this highly acclaimed volume examines every major aspect of Alzheimer disease--clinical, epidemiologic, structural, chemical, genetic, molecular, and therapeutic. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The broad coverage of AD in this book benefits clinicians, educators, investigators, and health administrators
目次
Part I. History 1. The Early Story of Alzheimer Disease Part II. Clinical Presentation 2. Clinical Presentation and Course of Alzheimer Disease 3. Noncognitive Symptoms of Alzheimer Disease 4. Neuropsychology of Alzheimer Disease 5. Clinical Genetics of Familial Alzheimer Disease 6. Brain Imaging in Alzheimer Disease Part III. Epidemiology 7. Epidemiology of Dementia and Alzheimer Disease 8. Alzheimer Disease Among Different Ethnic and Racial Groups Part IV. Confounding Disorders 9. Pick's Disease: Frontotemporal Dementia 10. Vascular Cognitive Impairment 11. The Prion Diseases 12. Dementia with Lewy Bodies Part V. Anatomic Pathology 13. The Neuropathology of Alzheimer Disease and the Structural Basis of Its Cognitive Alterations 14. The Cellular Basis of Cortical Disconnection in Alzheimer Disease and Related Dementing Conditions 15. The Neurobiology of Aging in Nonhuman Primates 16. Transgenic Animal Models in Alzheimer Disease Part VI. Biochemical Pathology 17. Alzheimer Disease: Neurochemical Aspects 18. Cholinergic Systems in Alzheimer Disease 19. Biology of -Amyloid Precursor Protein and the Mechanism of Alzheimer Disease 20. Molecular Genetics of Alzheimer Disease 21. Function and Dysfunction of the Presenilins 22. Apolipoprotein E and Alzheimer Disease 23. Apoptosis in Alzheimer Disease 24. Cell Biology of Tau and Cytoskeletal Pathology in Alzheimer Disease 25. Trophic Factor Therapy for Neuronal Death 26. Role of Inflammatory Processes and Microglia Activation in Alzheimer Disease 27. Oxidative Stress in Alzheimer Disease Part VII. Therapy 28. The Treatment of Noncognitive Symptoms 29. Clinical Trials in Alzheimer Diseas
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