This fully revised and well-documented new edition of the fields standard reference integrates the latest information on the scientific basis of respiratory medicine with its current practice. The book details the scientific principles of respiratory medicine and its foundation in basic anatomy, physiology, pharmacology, pathology, and immunology to provide a rationale and scientific approach to the more specialized clinical material covered in subsequent sections.
PART I. SCIENTIFIC PRINCIPLES OF RESPIRATORY MEDICINE Section A: Anatomy and Development of the Respiratory Tract 1. Anatomy of the Lungs 2. Lung Growth and Development 3. Genetic Basis of Lung Disease Section B: Respiratory Physiology 4. Ventilation, Blood Flow, and Gas Exchange 5. Respiratory System Mechanics 6. Pulmonary Circulation and Regulation of Fluid BalancE 7. Acid-Base Balance 8. Control of Breathing 9. Exercise Section C: Respiratory Pharmacology 10. Respiratory Pharmacology: General Pharmacologic Principles 11. Airway Pharmacology 12. Vascular Pharmacology Section D: Defense Mechanisms and Immunology 13. Pulmonary Surfactant 14. Mucus Secretion and Ion Transport in Airways 15. Deposition and Clearance 16. Monocytes, Macrophages, and Dentritic Cells of the Lung 17. Immune Recognition and Responses Section E: Respiratory Pathology and Inflammation 18. General Features of Respiratory Pathology 19. Inflammation, Injury, and Repair PART II. MANIFESTATIONS AND DIAGNOSIS OF RESPIRATORY DISEASE Section F: Manifestations of Respiratory Disease 20. Dyspnea 21. Cough 22. Chest Pain Section G. Diagnostic Evaluation 23. History and Physical Examination 24. Microbiologic Diagnosis of Lower Respiratory Tract Infection 25. Radiographic Techniques 26. Nuclear Medicine Techniques and Applications 27. Bronchoscopy, Lung Biopsy and other Diagnostic Procedures 28. Pulmonary Function Testing 29. Preoperative Evaluation 30. Evaluation of Respiratory Impairment/Disability PART III. CLINICAL RESPIRATORY MEDICINE Section H: Infectious Diseases of the Lungs 31. General Principles and Diagnostic Approach 32. Viral Infections 33. Pyogenic Bacterial Pneumonia, Lung Abscess, and Emphysema 34. Tuberculosis and Other Mycobacterial Diseases 35. Fungal Infections 36. Parasitic Diseases Section I. Obstructive Diseases 37. General Principles and Diagnostic Approach 38. Chronic Bronchitis and Emphysema 39. Asthma 40. Cystic Fibrosis 41. Bronchiectasis 42. Disorders of the Extrathoracic Airways, 43. Disorders of the Intrathoracic Airways Section J. Neoplasms of the Lungs 44. Biology of Lung Cancer 45. Epidemiology of Lung Cancer 46. Bronchogenic Carcinoma 47. Lymphoma, Lymphoproliferative Diseases, and Other Primary Malignant Tumors 48. Metastatic Malignant Tumors 49. Benign Tumors Section K. Disorders of the Pulmonary Circulation 50. General Principles and Diagnostic Approach 51. Pulmonary Thromboembolism 52. Pulmonary Vasculitis and Primary Pulmonary Hypertension 53. Pulmonary Arteriovenous Malformations and Other Pulmonary Vascular 54. Pulmonary Edema and Acute Lung Injury 55. Cor Pulmonale Section L. Infiltrative and Interstitial Lung Diseases 56. The Principles of and Approach to the Patient with Interstitial Lung Disease 57. Idiopathic Interstitial Penumonias 58. The Lungs and Connective Tissue Diseases 59. Sarcoidosis 60. Diffuse Alveolar Hemorrhage and Other Rare Infiltrative Disorders 61. Eosinophilic Lung Diseases 62. Lymphangioleiomyomatosis 63. Pulmonary Alveolar Proteinosis Section M. Environmental and Occupational Disorders 64. General Principles and Diagnostic Approach 65. Pneumoconioses 66. Occupational Asthma and Byssinosis 67. Hersensitivity S. Rose, MD, MPH 68. Air Pollution 69. Acute Pulmonary Responses to Toxic Exposures 70. Disorders of High Altitude 71. Diving Medicine 72. Drug-Induced Pulmonary Disease Section N. Disorders of the Pleura 73. General Principles and Diagnostic Approach 74. Pleural Effusion 75. Pneumothorax, Chylothorax, Hemothorax, and Fibrothorax 76. Tumors of the Pleura Section O. Disorders of the Mediastinum 77. General Principles and Diagnostic Approach 78. Pneumomediastinum and Mediastinitis 79. Tumors and Cysts of the Mediastinum Section P. Disorders in the Control of Breathing 80. Hypoventilation and Hyperventilation Syndromes 81. Sleep Disorders Section Q. Respiratory Manifestations of Extrapulmonary Disorders 82. Pulmonary Complications of Human Immunodeficiency Virus Infection 83. Pulmonary Complications of Organ Transplantation and Primary Immune Deficiencies 84. Pulmonary Complications of Heart Disease 85. Pulmonary Complications of Abdominal Disease 86. Pulmonary Complications of Hematologic Disease 87. Pulmonary Complications of Endocrine Disease 88. The Lungs in Obstetric and Gynecologic Disease 89. The Lungs and Neuromuscular Disease 90. The Lungs and Chest Wall Disease Section R. Respiratory Failure 91. Principles of Critical Care of Respiratory Failure 92. Acute Hypoxemic Respiratory Failure 93. Ventilatory Failure 94. Principles of Mechanical Ventilation 95. Ethics and Withdrawal of Life Support 96. Pulmonary Rehabilitation 97. Lung Transplantation Section S. Prevention and Control 98. Social and Behavioral Aspects of Prevention and Mgmt of Lung Disease 99. Community Measures: Public Policy and Education
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