Fetal origins of cardiovascular and lung disease

著者

• Barker, D. J. P. (David James Purslove)

書誌事項

Fetal origins of cardiovascular and lung disease

edited by David J. P. Barker

（Lung biology in health and disease, v. 151）

Dekker, c2001

注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

This watershed reference presents epidemiological, clinical, and experimental evidence that cardiovascular disease, Type 2 diabetes, and chronic lung disease originate through adaptations to the intrauterine environment. These new findings suggest that major chronic diseases in adult life may be prevented by improving the nutrition of girls and young women to promote healthy fetal development during pregnancy. Focusing on prenatal programming-the process whereby stimuli or insults at critical early periods of life have lasting effects-Fetal Origins of Cardiovascular and Lung Disease demonstrates the associations between low birthweight and cardiovascular disease and Type 2 diabetes in adults reveals the association between prenatal influences and hypertension and asthma in adult life describes pancreatic development in the fetus when the mother is malnourished or experiences metabolic disturbances during pregnancy examines the effects of undernutrition during gestation in experimental animal models discusses how the human fetus adapts to variations in maternoplacental nutrient supply details fetal influences on lipid metabolism, insulin sensitivity, the somatotrophic axis, andrenarche, and pubarche and more! Investigating when nurturing begins to influence and modulate gene expression, Fetal Origins of Cardiovascular and Lung Disease is critical for pulmonologists, cardiologists, pediatricians, neonatologists, obstetricians, internists, family practice physicians, and hospital interns and residents.

目次

Introduction David J. P. Barker Birth Weight, Blood Pressure, and Hypertension: Epidemiological Studies David A. Leon and Ilona Koupilova Mechanisms for In Utero Programming of Blood Pressure Christopher N. Martyn and Stephen E. Greenwald Low Birth Weight and the Emerging Burden of Renal Disease in the United States Daniel T. Lackland, Holly E. Bendall, Clive Osmond, and Brent M. Egan Intrauterine Nutrition: Its Importance During Critical Periods for Cardiovascular and Endocrine Development Joseph J. Hoet and Mark A. Hanson Physiological Development of the Cardiovascular System In Utero Kent L. Thornburg Non-Insulin-Dependent Diabetes and Obesity David I. W. Phillips Metabolic Alterations After Early Growth Retardation Susan Ozanne, B. J. Jennings, and C. Nicholas Hales Growth, Metabolic, and Endocrine Adaptations to Fetal Undernutrition Jane E. Harding and Peter D. Gluckman The Role of Hormones in Intrauterine Development Abigail L. Fowden and Alison J. Forhead The Hypothalamic-Pituitary-Adrenal and Hypothalamic-Pituitary-Gonadal Axes in Early Life: Problems and Perspectives Stephen G. Matthews, David I. W. Phillips, John R. G. Challis, David B. Cox, Eric Jackson Thomas, Caroline McMillen, S. J. Lye, Roger B. McDonald, E. Marelyn Wintour, Janna L. Morrison, and Deborah M. Sloboda Reduced Fetal Growth and Pediatric Endocrinopathies Francis de Zegher, Inge Francois, and Lourdes Ibanez Maternal Nutrition and Fetal Development: Implications for Fetal Programming Keith M. Godfrey Maternal and Placental Influences that Program the Fetus: Experimental Findings Jeffrey S. Robinson, Caroline McMillen, Lisa Edwards, Karen Kind, Kathryn L. Gatford, and Julie Owens Fetal Origins of Lung Disease John O. Warner and Catherine A. Jones The Nutrition Transition and its Implications for the Fetal Origins Hypothesis Barry M. Popkin Effects of Maternal Nutrition and Metabolism on the Developing Endocrine Pancreas: Experimental Findings B. Reusens and C. Remacle

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詳細情報

• NII書誌ID(NCID): BA48892198
• ISBN:
  • 082470391X
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xxi, 398 p.
• 大きさ: 24 cm
• 親書誌ID:
  • BA00563007