Gaba in the nervous system : the view at fifty years

著者

• Martin, David L.
• Olsen, Richard W.

書誌事項

Gaba in the nervous system : the view at fifty years

editors, David L. Martin, Richard W. Olsen

Lippincott Williams & Wilkins, c2000

注記

Includes bibliographical references and index

内容説明・目次

内容説明

GABA in the Nervous System summarizes recent advances in understanding the role of GABA as a neurotransmitter. First discovered as an inhibitory signal in 1950, GABA may also fulfill a decisive role in diseases such as Parkinson's and Alzheimer's, stroke, and other clinical problems. This book provides a comprehensive understanding of GABA at both the molecular and systemic level. Each chapter provides a balanced view of current knowledge while referencing historical discoveries during the last half-century

目次

• Adventures with GABA:Fifty Years On
• Mechanisms Controlling GABA Synthesis and Degradation in the Brain
• Cytoplasmic Membrane Transporters for GABA
• Uptake and Storage of GABA in Synaptic Vesicles
• GABA Chemistry:Analogs of GABA as Therapeutic and Investigational Agents
• Function of GABA Receptors:Insights from Mutant and Knockout Mice
• The Benzodiazepine Site of GABA Receptors
• Pharmacologic Subtypes of GABA Receptors Based on Subunit Composition
• Functional Domains of GABA Receptors
• Kinetic Properties of GABA Receptor Channels
• Alcohol and General Anesthetic Actions on the GABA Receptor
• Regulation of GABA Receptors by Protein Phosphorylation
• Neurosteroids and GABA Receptor Plasticity
• GABA Receptors:Structure and Function
• GABA Emerges as a Developmental Signal during Neurogenesis of the Rat Central Nervous System
• GABA in the Basal Ganglia
• Epilepsy
• GABAergic Interneuronal Networks in the Hippocampus
• GABA Neurons of the Hippocampal Formation:Localization, Vulnerability, and Plasticity
• GABA Neurons of the Neocortex
• GABA Receptor Diversity:A View from the Cerebellum
• GABAergic Inhibition in the Cerebellar System
• Neuromodulation of GABA in Developing and Mature Hypothalamic Neurons
• GABA in the Mammalian Spinal Cord
• GABA in the Retina
• The Role of Glutamic Acid Decarboxylase and GABA in the Pancreas and Diabetes
• Index

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA4948233X
• ISBN:
  • 0781722675
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Philadelphia
• ページ数/冊数: xiii, 510 p.
• 大きさ: 26 cm
• 分類:
  • LCC : QP563
  • NLM : QU 60 G1118 2000
  • DC21 : 612.8/042
• 件名:
  • LCSH : GABA -- Physiological effect
  • LCSH : GABA -- Receptors
  • LCSH : Amino acid neurotransmitters
  • MESH : GABA -- Physiology
  • MESH : Central Nervous System -- physiology
  • MESH : Receptors, GABA -- physiology