Bioinformatics : sequence and genome analysis
著者
書誌事項
Bioinformatics : sequence and genome analysis
Cold Spring Harbor Laboratory Press, c2001
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The application of computational methods to DNA and protein science is an exciting development in biology. "Bioinformatics: Sequence and Genome Analysis" is a comprehensive introduction to this emerging field of study. The book has many valuable features. It is written for biologists who want to understand methods of sequence and structure analysis and how the necessary computer programs work. Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and illustrated. Underlying algorithms and assumptions are also explained for the non-specialist, and examples are presented in simple numerical terms rather than complex formulas and notation. Theoretical underpinnings are linked to biological problems and their solutions, while extensive tables provide descriptions and Web sources for a broad range of publicly available software. Based on the author's experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is an educational book, useful as a laboratory reference for investigators and also as a teaching reference for graduate and undergraduate students.
目次
- Historical introduction and overview
- collecting and storing sequences in the laboratory
- alignment of pairs of sequences
- multiple sequence alignment
- prediction of RNA secondary structure
- phylogenetic prediction
- database searching for similar sequences
- gene prediction
- protein classification and structure prediction
- genome analysis.
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