Genetic models in cardiorespiratory biology

Author(s)

Bibliographic Information

Genetic models in cardiorespiratory biology

edited by Gabriel G. Haddad, Tian Xu

(Lung biology in health and disease, v. 156)

M. Dekker, c2001

Available at  / 14 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Focusing on the latest breakthroughs in genetic analysis and manipulation, Genetic Models in Cardiorespiratory Biology extensively details how genetic model systems facilitate better comprehension of mammalian and human biology and disease. Highlights studies of Drosophila melanogaster, Caenorhabditis (C.) elegans, zebrafish, and transgenic mouse models-revealing high functional conservation to homologous genes in humans and promoting insight into biological processes! Applying technical and research advances toward the discovery of potential therapeutic gene agents, Genetic Models in Cardiorespiratory Biology summarizes current knowledge of cellular movements underlying heart tube morphogenesis and the role of genetic analysis in identifying critical molecules in cardiac development and formation illustrates the heterogeneity of tissue responses to hypoxia with genetic and invertebrate examples describes the control and influence of oxygen homeostasis by hypoxia-inducible factor-1 (HIF-1) on embryogenesis, physiology, and disease pathogenesis uses the Drosophila model to show the interface between global specification of cardiac competence and cell-type specific differentiation within the developing embryo studies over 40 mutations in zebrafish and mouse genes detailing vertebrate heart development, distinguishing novel genes in cardiac development, and delineating signaling pathways demonstrates the fundamental asymmetrical structure of the node monocilium through leftright asymmetry abnormalities considers the role and relationship of apoptosis in vertebrates and to the development of immune and cardiac systems, autoimmune and cardiac diseases, and cancer presents evolving paradigms in vasculogenesis and angiogenesis and the importance of the vascular endothelial growth factor (VEGF) family and much more! Written by nearly 25 experts in the field and supplemented with more than 1600 literature references, drawings, photographs, and tables, Genetic Models in Cardiorespiratory Biology satisfies the reference needs of pulmonologists and pulmonary disease specialists, geneticists, cardiologists, physiologists, biochemists, molecular and cell biologists, neonatologists and pediatricians, pathologists, anatomists, and graduate-level and medical school students in these disciplines.

Table of Contents

Fundamentals of Capillary Electrochromatography Ute Pyell Membrane Extraction Techniques for Sample Preparation Jan Ake Joensson and Lennart Mathiasson Design of Rapid Gradient Methods for the Analysis of Combinatorial Chemistry Libraries and the Preparation of Pure Compounds Uwe D. Neue, Judy L. Carmody, Yung-Fong Cheng, Ziling Lu, Charles H. Phoebe, and Thomas E. Wheat Molecularly Imprinted Extraction Materials for Highly Selective Sample Clean- Up and Analyte Enrichment Francesca Lanza and Boerje Sellergren Biomembrane Chromatography: Application to Purification and Biomolecule- Membrane Interactions Tzong-Hsien Lee and Marie-Isabel Aguilar Transformation of Analytes for Electrochemical Detection: A Review of Chemical and Physical Approaches Mark J. Rose, Susan M. Lunte, Robert G. Carlson, and John F. Stobaugh High-Performance Liquid Chromatography: Trace Metal Determination and Speciation Corrado Sarzanini Temperature-Responsive Chromatography Hideko Kanazawa, Yoshikazu Matsushima, and Teruo Okano Carrier Gas in Capillary Gas-Liquid Chromatography V. G. Berezkin Catechins in Tea: Chemistry and Analysis Christina S. Robb and Phyllis R. Brown

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Details

  • NCID
    BA51635160
  • ISBN
    • 0824705122
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    New York
  • Pages/Volumes
    xix, 457 p.
  • Size
    24 cm
  • Parent Bibliography ID
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