CiNii 図書 - Biological responses to DNA damage

Living cells have evolved many ways of coping with metabolic events and environmental influences that damage DNA. These mechanisms, and the frequent progression to cancer that results when they go awry, are reviewed in this volume by authors from over 60 of the world's leading laboratories. The topics discussed include DNA repair, mutagenesis and other damage-tolerance functions, checkpoint control, apoptosis, and adaptation. They draw from studies on human and yeast cells. Contemporary, but with a historical perspective, this volume has the depth and lasting value typical of this series and should prove useful reading for investigators of DNA replication, cell cycle control, and tumorigenesis.

Mutation response and error bypass, G.C. Walker, M. Radman, P.L. Foster, M.F. Goodman, E.C. Friedberg, L. Prakash, C.W. Lawrence, F. Hanaoka, T.A. Kunkel
base recognition and excision repair, E.T. Kool, G.L. Verdine, J.A. Tainer, T. Lindahl, E. Seeberg, S.H. Wilson, A. Sancar
nucleotide excision repair, R.D. Wood, P.C. Hanawalt, G. Mer, P.K. Cooper
mismatch repair, R. Fishel, W. Yang, K. Morikawa, J.H. Miller
telomeres and the stability of DNA ends, E.H. Blackburn, T. de Lange, C.W. Greider, D.E. Gottschling, L. Guarente, J.E. Haber, S.C. West
damage control during replication and mitosis, P. Nurse, J.F.X. Diffley, R. Rothstein, E.J. Foss, P. Russell, P.K. Sorger, C.L. Rieder
genome stability and checkpoint control, J.F. Ward, L.D. Samson, F.W. Alt, J.H.J. Petrini, S.J. Elledge, S.P. Jackson, R.D. Kolodner, T. Weinert, M. Yanagida, A.M. Carr, R.S. Weiss, M.O. Hengartner
p53 and the DNA damage response, A.J. Levine, D. Lane, C. Prives, S.W. Lowe, G. Wahl
DNA damage and cancer progression, M.B. Kastan, Y. Shiloh, D.M. Livingston, J.H. Chung, M. Jasin, S.A. Leadon, A.R. Venkitaraman, I.D. Hickson, Z.-Q. Wang
summary, E.C. Friedberg.

巻冊次: : paper ISBN 9780879696061

内容説明

Living cells have evolved many ways of coping with metabolic events and environmental influences that damage DNA. These mechanisms, and the frequent progression to cancer that results when they go awry, are reviewed in this volume by authors from over sixty of the world's leading laboratories. The topics discussed include DNA repair, mutagenesis and other damage-tolerance functions, checkpoint control, apoptosis, and adaptation. They draw from studies on human and yeast cells. Current, but with a valuable historical perspective, this volume has the depth and lasting value typical of this most prestigious series and is essential reading for investigators of DNA replication, cell cycle control, and tumorigenesis.

Symposium Participants Foreword Mutation Response and Error Bypass (G.C. Walker, M. Radman, P.L. Foster, M.F. Goodman, E.C. Friedberg, L. Prakash, C.W. Lawrence, F. Hanaoka, T.A. Kunkel) Base Recognition and Excision Repair (E.T. Kool, G.L. Verdine, J.A. Tainer, T. Lindahl, E. Seeberg, S.H. Wilson, A. Sancar) Nucleotide Excision Repair (R.D. Wood, P.C. Hanawalt, G. Mer, P.K. Cooper) Mismatch Repair (R. Fishel, W. Yang, K. Morikawa, J.H. Miller) Telomeres and the Stability of DNA Ends (E.H. Blackburn, T. de Lange, C.W. Greider, D.E. Gottschling, L. Guarente, J.E. Haber, S.C. West) Damage Control during Replication and Mitosis (P. Nurse, J.F.X. Diffley, R. Rothstein, E.J. Foss, P. Russell, P.K. Sorger, C.L. Rieder) Genome Stability and Checkpoint Control (J.F. Ward, L.D. Samson, F.W. Alt, J.H.J. Petrini, S.J. Elledge, S.P. Jackson, R.D. Kolodner, T. Weinert, M. Yanagida, A.M. Carr, R.S. Weiss, M.O. Hengartner) p53 and the DNA Damage Response (A.J. Levine, D. Lane, C. Prives, S.W. Lowe, G. Wahl) DNA Damage and Cancer Progression (M.B. Kastan, Y. Shiloh, D.M. Livingston, J.H. Chung, M. Jasin, S.A. Leadon, A.R. Venkitaraman, I.D. Hickson, Z.-Q. Wang) Summary (E.C. Friedberg)

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Biological responses to DNA damage

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