Pharmacogenomics

著者

• Kalow, Werner
• Meyer, U. A.
• Tyndale, R. F.

書誌事項

Pharmacogenomics

edited by Werner Kalow, Urs A. Meyer, Rachel F. Tyndale

（Drugs and the pharmaceutical sciences, v. 113）

M. Dekker, Inc., c2001

注記

Includes bibliographical references and index

内容説明・目次

内容説明

"Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."

目次

• Historical aspects of pharmacogenomics
• pharmacogenomics, biomarkers and the promise of personalized medicine
• current status - pharmacogenetics/drug metabolism
• pharmacogenetics -receptors
• pharmacogenetics of drug transporters
• interethnic differences in drug response
• pharmacogenetics - clinical viewpoints
• tools of the trade - the technologies and challenges of pharmacogenetics
• molecular diagnostics and development of biotechnology-based diagnostics
• technologies for the analysis of single-nucleotide polymorphisms - an overview
• multiplex fluorescent minisequencing applied to the typing of genes encoding drug-metabolizing enzymes
• multiplex genotyping by specialized mass spectrometry
• serial analysis of gene expression -transcriptional insights into functional biology
• proteomics
• bioinformatics - WWW resources
• applied bioinformatics
• mapping of disease loci
• positional cloning and disease gene identification
• general conclusions and future directions.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA5268821X
• ISBN:
  • 0824705440
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xi, 403 p.
• 大きさ: 24 cm
• 親書誌ID:
  • BA03948165