Heart failure : pathogenesis and treatment
著者
書誌事項
Heart failure : pathogenesis and treatment
Martin Dunitz, 2002
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Edited by eminent leaders in the field and with contributions from key international experts, Heart Failure: Pathogenesis and Management explores all aspects of myocardial disorders. It begins with an examination of the basic concepts of myocardial architecture and physiology, and then considers the pathogenetic mechanisms involved in the evolution of cardiomyopathic disorders. The third section explores secondary disorders, describing the full range of common pathogenesis. It provides practical guidance on the management of cardiomyopathies and reviews of the latest non-transplant surgical intervention techniques in the management of end-stage cardiomyopathies.
目次
Section I. Basic Concepts Of Myocardial Architecture And Physiology. Cellular And Molecular Basis Of Myocardial Contraction The Mechanics, Determinants And Regulation Of Cardiac Contraction. Myocardial Energetics And Cardiac Contractility. Transcriptional Circuits Mediating Cardiac Hypertrophy And Heart Failure. Histopathologic Basis Of Cardiomyopathic Disorders. Classification And Nomenclature Of Cardiomyopathic Disorders. Section II. Pathogenetic Mechanisms On Evolution Of Cardiomyopathic Disorders. Gene Mutations That Cause Hypertrophic Cardiomyopathy. Abnormalities Of Calcium Homeostasis And Defective Excitation-Contraction Coupling In Cardiomyopathy. Local Hormonal Adaptations Of The Myopathic Hearts. Molecular Basis Of Cardiac Hypertrophy. Endothelial In Myocardial Remodeling And Failure. Mitochondrial Abnormalities In Cardiomyopathy. Altered Receptor-Mediated Signaling In Cardiomyopathy. Role Of Altered Ion-Channel Expression In Sudden Death In Heart Failure. Viral Myocardial Disease. Auto-Immune Basis of Myocardial Disease. Myocardial Inflammation and Myocellular Damage. Apoptosis in Congestive Heart Failure. Myocellular And Myocardial Extracellular Matrix Remodeling. Section III. Pathogenetic Basis of Secondary Cardiomyopathic Disorders. Myocardial Involvement in Ischemic Heart Disease: Role of Hibernating Myocardium. Hypertensive Heart Disease and Progressive Myocellular Loss. The Myocardium in Diabetes Mellitus. Infective Disease Of The Myocardium. Molecular Basis Of Post-Infective Auto-Immune Myocardial Disorders. Alcohol-Induced Myocardial Damage: Reversibility and Clinical Implications. HIV-Related Cardiomyopathic Disease. Cardiac Involvement in Systemic Disorders. Iatrogenic Myocardial Dysfunction. Section IV. Pathogenetic Basis Of Management of Cardiomyopathies. Newer Pharmacologic Options in Myocardial Diseases. Targeting Genes and Modulating Signal Transduction in Cardiomyopathies. Congestive Heart Failure: Contemporary Medical Therapy. Relentlessly Progressive Congestive Heart Failure: Can it be Prevented? Spatial Orientation of the Ventricular Muscle Band and Approach to Partial Ventriculotomy in Heart Failure. Section V. Non-Transplant Surgery for End-Stage Cardiomyopathy. Exploiting our Understanding of Pathogenetic Mechanisms in Developing Surgical Interventions. Coronary Revascularization as an Alternative to Transplantation. Left Ventricular Remodeling and Mitral Valve Repair. Mechanical Circulatory Support and Myocyte Recovery.
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